Rajput M A, Richey H M, Bush B A, Glendening D L, Matthews J I
Pulmonary Disease Service, Brooke Army Medical Center, San Antonio, Tex.
Arch Intern Med. 1989 Jan;149(1):83-5.
Invasive hemodynamic monitoring is frequently required in the management of patients in intensive care units. A fiberoptic flow-directed thermal dilution pulmonary artery catheter capable of continuously monitoring the mixed venous saturation, while more expensive than a conventional pulmonary artery catheter, theoretically could result in better patient care, and might be cost-effective if it resulted either in fewer blood tests being ordered or in less time in the intensive care unit. To test this hypothesis, we designed a randomized trial in our Medical Intensive Care Unit to compare a standard pulmonary artery catheter with a fiberoptic catheter. Twenty-six patients received a standard catheter and 25 patients received the fiberoptic catheter. There were no statistical differences between the groups in age, time in the intensive care unit, number of tests ordered, hours of mechanical ventilator therapy, hours of vasoactive drug therapy, or mortality rate. The only statistically significant differences between the groups were that (1) the fiberoptic catheter required a longer insertion time and (2) there were more technical problems in consistently obtaining the wedge pressure in the patients with the fiberoptic catheters. We conclude that routine substitution of a fiberoptic catheter for the standard pulmonary artery catheter is not indicated.
在重症监护病房患者的管理中,经常需要进行有创血流动力学监测。一种能够连续监测混合静脉血氧饱和度的光纤导向热稀释肺动脉导管,虽然比传统肺动脉导管更昂贵,但理论上可能会带来更好的患者护理,如果它能减少血液检查的次数或缩短在重症监护病房的时间,可能具有成本效益。为了验证这一假设,我们在我们的内科重症监护病房设计了一项随机试验,比较标准肺动脉导管和光纤导管。26名患者接受了标准导管,25名患者接受了光纤导管。两组在年龄、在重症监护病房的时间、检查次数、机械通气治疗时间、血管活性药物治疗时间或死亡率方面没有统计学差异。两组之间唯一具有统计学意义的差异是:(1)光纤导管插入时间更长;(2)在使用光纤导管的患者中,持续获取楔压时出现的技术问题更多。我们得出结论,不建议常规用光纤导管替代标准肺动脉导管。