Paprottka Felix J, Krezdorn Nicco, Narwan Mustafa, Turk Marvee, Sorg Heiko, Noah Ernst Magnus, Hebebrand Detlev
Department of Plastic, Aesthetic, Reconstructive and Hand Surgery, AGAPLESION Diakonieklinikum Rotenburg, Elise-Averdieck-Straße 17, 27356, Rotenburg (Wümme), Germany.
Harvard Medical School, Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.
Aesthetic Plast Surg. 2018 Feb;42(1):310-321. doi: 10.1007/s00266-017-1002-0. Epub 2017 Nov 9.
The literature reports many cases of cutaneous malignancy in the setting of skin tattoos. In this study, we review the reported incidence of and risk factors for tattoo-associated skin cancer.
A PubMed literature review was performed for all cases of tattoo-associated skin cancer, including squamous cell carcinoma, basal cell carcinoma, malignant melanoma, keratoacanthoma, and other rare skin malignancies (source: PubMed/until June 2017).
The authors identified 51 publications and 63 total cases of tattoo-associated skin cancer. We also report on a single new case of tattoo-associated skin cancer observed at one of our co-authors' institutions. Among these 64 total cases, 58% were associated with black and blue inks and 34% were associated with red ink.
Overall, while the strength of association remains unclear, the literature reports many cases of tattoo-associated skin cancer. Among these cases, black, blue, and red inks were particularly worrisome for their carcinogenic potential.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
文献报道了许多皮肤纹身相关的皮肤恶性肿瘤病例。在本研究中，我们回顾了纹身相关皮肤癌的报道发病率及危险因素。
通过PubMed文献检索，收集所有纹身相关皮肤癌病例，包括鳞状细胞癌、基底细胞癌、恶性黑色素瘤、角化棘皮瘤及其他罕见皮肤恶性肿瘤（来源：PubMed/截至2017年6月）。
作者共识别出51篇文献及63例纹身相关皮肤癌病例。我们还报告了一位共同作者所在机构观察到的1例新的纹身相关皮肤癌病例。在这64例病例中，58%与黑色和蓝色墨水有关，34%与红色墨水有关。
总体而言，虽然关联强度尚不清楚，但文献报道了许多纹身相关皮肤癌病例。在这些病例中，黑色、蓝色和红色墨水因其致癌潜力尤其令人担忧。
证据级别IV：本刊要求作者为每篇文章指定证据级别。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南www.springer.com/00266 。
