Cohen Philip R, Erickson Christof P, Uebelhoer Nathan S, Calame Antoanella
San Diego Family Dermatology, National City, California, USA.
Department of Dermatology, Touro University California College of Osteopathic Medicine, Vallejo, California, USA.
Biomed Hub. 2020 Jul 8;5(2):2055-2062. doi: 10.1159/000508208. eCollection 2020 May-Aug.
Tattoos may be associated with medical complications including, albeit rarely, skin cancer. The features of a 46-year-old man who developed a basal cell carcinoma within a tattoo on his left scapula are described and the characteristics of the other 13 patients (7 men and 6 women) with tattoo-associated basal cell carcinoma are reviewed. The tumor usually occurs on the sun-exposed skin of individuals aged 60 years and older whose tattoo has often been present for 20 years or more. The pathogenesis of a basal cell carcinoma developing within a tattoo may merely be a coincidence. However, there is supporting evidence that the tattoo and the subsequent basal cell carcinoma may be coincident events whereby either tattoo injection-associated trauma or the tattoo pigments and dyes (in their native state or after ultraviolet radiation alteration) or both have a carcinogenic impact on the development of the basal cell carcinoma at that location.
纹身可能与包括皮肤癌（尽管很少见）在内的医学并发症相关。本文描述了一名46岁男性在左肩胛骨纹身内发生基底细胞癌的特征，并回顾了其他13例（7名男性和6名女性）与纹身相关的基底细胞癌患者的特征。肿瘤通常发生在60岁及以上人群暴露于阳光下的皮肤上，其纹身通常已存在20年或更长时间。纹身内发生基底细胞癌的发病机制可能仅仅是巧合。然而，有证据支持纹身与随后发生的基底细胞癌可能是同时发生的事件，即纹身注射相关的创伤或纹身颜料和染料（处于原始状态或经紫外线辐射改变后）或两者对该部位基底细胞癌的发生都有致癌作用。
