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一例形态独特、表现为难治性溃疡的食管放线菌病。

A case of esophageal actinomycosis with a unique morphology presenting as a refractory ulcer.

作者信息

Fukuda Sho, Watanabe Noboru, Domen Takahiro, Ishioka Mitsuaki, Sawaguchi Masayuki, Ohba Reina, Shiga Hisashi, Matsuhashi Tamotsu, Jin Mario, Iijima Katsunori

机构信息

Department of Gastroenterology, Akita University Graduate School of Medicine, Hondo 1-1-1, Akita, Akita, Japan.

出版信息

Clin J Gastroenterol. 2018 Feb;11(1):38-41. doi: 10.1007/s12328-017-0797-1. Epub 2017 Nov 9.

DOI:10.1007/s12328-017-0797-1
PMID:29124648
Abstract

A 60-year-old man presented with odynophagia after bronchial artery infusion chemotherapy for pulmonary metastasis of hepatocellular carcinoma. Esophagogastroduodenoscopy (EGD) revealed an esophageal ulcer in the middle thoracic esophagus. An esophageal biopsy demonstrated no malignancy. However, the symptoms had not improved after a month. EGD was performed again and showed a white cord lump at the bottom of the same esophageal ulcer identified before, showing no improving tendency. A repeated biopsy of the lump revealed actinomycosis, and the symptoms were improved by the oral administration of ampicillin. We herein report a case in which esophageal actinomycosis with a unique morphology of refractory esophageal ulcer was rapidly improved by the administration of antibiotics.

摘要

一名60岁男性在接受支气管动脉灌注化疗治疗肝细胞癌肺转移后出现吞咽痛。食管胃十二指肠镜检查(EGD)显示胸段食管中段有一处食管溃疡。食管活检未发现恶性病变。然而,一个月后症状并未改善。再次进行EGD检查,发现在之前确定的同一食管溃疡底部有一个白色索状肿块,且无改善趋势。对该肿块再次活检显示为放线菌病,口服氨苄西林后症状得到改善。我们在此报告一例食管放线菌病病例,其具有难治性食管溃疡的独特形态,通过抗生素治疗迅速得到改善。

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本文引用的文献

1
Esophageal Actinomycoses Mimicking Malignancy.酷似恶性肿瘤的食管放线菌病
Ann Thorac Surg. 2016 May;101(5):1967-70. doi: 10.1016/j.athoracsur.2015.07.044.
2
Dysphagia caused by esophageal actinomycosis.食管放线菌病引起的吞咽困难。
Clin Gastroenterol Hepatol. 2015 Jun;13(6):A21-2. doi: 10.1016/j.cgh.2015.01.012. Epub 2015 Jan 24.
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A rare presentation of esophageal actinomycosis in an immunocompetent patient.免疫功能正常患者食管放线菌病的罕见表现。
Endoscopy. 2013;45 Suppl 2 UCTN:E181-2. doi: 10.1055/s-0033-1344067. Epub 2013 Jun 25.
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A rare cause of esophageal strictures: Actinomyces.食管狭窄的罕见病因:放线菌。
Gastrointest Endosc. 2012 May;75(5):1111-2. doi: 10.1016/j.gie.2011.05.047. Epub 2011 Aug 5.
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Esophageal actinomycosis in a fifty-three-year-old man with HIV: case report and review of the literature.一名 53 岁感染 HIV 的男性患有食管放线菌病:病例报告及文献复习。
AIDS Patient Care STDS. 2010 Feb;24(2):73-8. doi: 10.1089/apc.2009.0185.
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[Esophageal actinomycosis].[食管放线菌病]
Rev Esp Enferm Dig. 2009 May;101(5):372-3.
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Esophageal actinomycosis.
Adv Ther. 2006 Jul-Aug;23(4):623-6. doi: 10.1007/BF02850050.
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Actinomycosis mimicking anastomotic recurrent esophageal cancer on PET-CT.放线菌病在PET-CT上表现类似吻合口复发性食管癌。
Clin Nucl Med. 2006 Oct;31(10):646-7. doi: 10.1097/01.rlu.0000238193.34543.b9.
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[Esophagus actinomycosis causing upper gastrointestinal bleeding].[食管放线菌病导致上消化道出血]
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