Zhang Allison N, Guss Debra, Mohanty Smruti R
Division of Gastroenterology and Hepatobiliary Diseases, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, 11215, USA.
Case Rep Gastrointest Med. 2019 Jan 2;2019:7182976. doi: 10.1155/2019/7182976. eCollection 2019.
species are Gram positive anaerobic or microaerophilic bacteria that are part of the human flora in the oropharyngeal, gastrointestinal, and genitourinary tract. In the presence of a mucosal injury, they can become pathogenic and infect the underlying tissue without respect for tissue planes, leading to abscesses, fistulas, and sinus tracts. Through contiguous and hematogenous spread, virtually any organ can become infected. The presentation can be myriad and often mimics tumors, tuberculosis, or other more common infections and inflammatory conditions. While the cervicofacial region is the most common site of infection, involvement of the esophagus is unusual. Esophageal actinomycosis mostly occurs in patients with compromised immunity or prior esophageal injuries. Occurrence in immunocompetent individuals without risk factors is exceedingly rare. We report a case of esophageal actinomycosis complicated by an esophageal stricture in a patient with no apparent predisposing conditions.
放线菌属是革兰氏阳性厌氧菌或微需氧菌，是人类口咽、胃肠道和泌尿生殖道菌群的一部分。在存在黏膜损伤的情况下，它们可成为病原体并感染深层组织，而不考虑组织层面，导致脓肿、瘘管和窦道。通过直接蔓延和血行播散，几乎任何器官都可能被感染。临床表现多种多样，常类似于肿瘤、结核病或其他更常见的感染和炎症性疾病。虽然颈面部区域是最常见的感染部位，但食管受累并不常见。食管放线菌病大多发生在免疫功能低下或既往有食管损伤的患者中。在没有危险因素的免疫功能正常个体中发生极为罕见。我们报告一例无明显易感因素的患者发生食管放线菌病并伴有食管狭窄的病例。
