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紫外线对白癜风的影响。

Impact of Ultraviolet Light on Vitiligo.

作者信息

Singh Rasnik K

机构信息

David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA, 90095, USA.

出版信息

Adv Exp Med Biol. 2017;996:55-60. doi: 10.1007/978-3-319-56017-5_5.

DOI:10.1007/978-3-319-56017-5_5
PMID:29124690
Abstract

Vitiligo is a disorder of the melanocytes that results in a dynamic spectrum of skin depigmentation. Its etiology is complex and multifactorial, with data supporting several different hypotheses. Given its prominent phenotype, vitiligo has a significant negative impact on quality of life. Coupled with the chronic and incurable nature of the disease, this presents a formidable treatment challenge. Several treatment modalities have been instituted over the years, with varying efficacy. This chapter focuses on the use of ultraviolet light in vitiligo as an established therapeutic option.

摘要

白癜风是一种黑素细胞疾病,可导致皮肤色素脱失呈现动态变化。其病因复杂且具有多因素性,有数据支持多种不同假说。鉴于其显著的表型,白癜风对生活质量有重大负面影响。再加上该疾病的慢性和不可治愈性,这带来了巨大的治疗挑战。多年来已采用多种治疗方式,疗效各异。本章重点介绍紫外线在白癜风治疗中的应用,这是一种既定的治疗选择。

相似文献

1
Impact of Ultraviolet Light on Vitiligo.紫外线对白癜风的影响。
Adv Exp Med Biol. 2017;996:55-60. doi: 10.1007/978-3-319-56017-5_5.
2
Activation of melanoblasts and melanocytes after treatment with monochromatic excimer light and narrowband-ultraviolet B of skin of vitiligo patients.白癜风患者皮肤经单色准分子光和窄谱中波紫外线治疗后黑素细胞原的激活。
Int J Dermatol. 2019 Feb;58(2):210-217. doi: 10.1111/ijd.14216. Epub 2018 Sep 6.
3
The effect of NB-UVB on noncultured melanocyte and keratinocyte transplantation in treatment of generalized vitiligo using two different donor-to-recipient ratios.窄谱中波紫外线对非培养黑素细胞和角质形成细胞移植治疗泛发性白癜风的效果:采用两种不同供受比
J Cosmet Dermatol. 2019 Apr;18(2):638-646. doi: 10.1111/jocd.12759. Epub 2018 Oct 2.
4
Low-dose UVB therapy is comparable with conventional UVB phototherapy for treatment of vitiligo: A pilot study.低剂量紫外线B光疗法与传统紫外线B光疗治疗白癜风疗效相当:一项初步研究。
J Dermatol Sci. 2018 Nov;92(2):218-220. doi: 10.1016/j.jdermsci.2018.08.006. Epub 2018 Aug 31.
5
Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients.预测窄谱中波紫外线光疗治疗白癜风反应率的模型:对 579 例患者的回顾性队列研究。
Acta Derm Venereol. 2018 Apr 16;98(4):416-420. doi: 10.2340/00015555-2889.
6
Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study.四氢姜黄素乳膏联合靶向窄谱中波紫外线光疗治疗白癜风:一项初步随机对照研究。
Photomed Laser Surg. 2010 Oct;28(5):679-84. doi: 10.1089/pho.2009.2637.
7
Repigmentation patterns induced by NB-UVB and their relationship with melanocytic migration and proliferation in vitiligo.窄谱中波紫外线诱导的复色模式及其与白癜风中黑素细胞迁移和增殖的关系
Photodermatol Photoimmunol Photomed. 2016 Sep;32(5-6):269-275. doi: 10.1111/phpp.12275. Epub 2016 Oct 5.
8
Vitiligo management: combination of surgical treatment and phototherapy under reflectance confocal microscopy monitoring.白癜风的治疗:反射共聚焦显微镜监测下的手术治疗与光疗相结合。
Eur Rev Med Pharmacol Sci. 2020 Jul;24(13):7366-7371. doi: 10.26355/eurrev_202007_21904.
9
Combined therapy for resistant vitiligo lesions: NB-UVB, microneedling, and topical latanoprost, showed no enhanced efficacy compared to topical latanoprost and NB-UVB.针对顽固性白癜风皮损的联合治疗:窄谱中波紫外线(NB-UVB)、微针治疗和外用拉坦前列素,与外用拉坦前列素和NB-UVB相比,未显示出增强的疗效。
Dermatol Ther. 2016 Sep;29(5):312-316. doi: 10.1111/dth.12363. Epub 2016 Jun 30.
10
Simultaneous improvement and worsening of vitiligo lesions during the course of NB-UVB phototherapy; vitiligo may not act as one unit.窄谱中波紫外线(NB-UVB)光疗过程中白癜风皮损同时出现改善和加重的情况;白癜风可能并非一个整体。
Dermatol Ther. 2017 Jan;30(1). doi: 10.1111/dth.12420. Epub 2016 Sep 9.

引用本文的文献

1
Vitiligo: From mechanisms of disease to treatable pathways.白癜风:从发病机制到可治疗途径
Skin Health Dis. 2024 Sep 30;4(6):e460. doi: 10.1002/ski2.460. eCollection 2024 Dec.