Sharma Vinod Kumar, Sahni Kanika
Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
Adv Exp Med Biol. 2017;996:111-122. doi: 10.1007/978-3-319-56017-5_10.
Skin colour (specifically in relation to its melanin content and composition) has a marked influence on its interaction with ultraviolet light. Eumelanin has mainly photoprotective properties while pheomelanin has the ability to cause formation of reactive oxygen species. This difference is responsible for the difference in incidence and presentation of various idiopathic photodermatoses in dark skinned patients compared to those with lighter skin types. Certain conditions are peculiar to darker skins including pin point popular variant of polymorphous light eruption. These differences are discussed in this chapter while also highlighting the challenges faced in performing phototesting in patients with dark skin.
肤色(特别是与其黑色素含量和组成相关)对其与紫外线的相互作用有显著影响。真黑素主要具有光保护特性,而褐黑素具有引发活性氧形成的能力。与皮肤较浅类型的患者相比,这种差异导致深色皮肤患者各种特发性光皮肤病的发病率和表现有所不同。某些情况在深色皮肤中较为特殊,包括多形性日光疹的点状丘疹变体。本章将讨论这些差异,同时也强调在深色皮肤患者中进行光试验所面临的挑战。