Issa Claire Michael
Endocrinology Consultant, Ain Wazein Medical Village, Lebanon- Mount of Lebanon-Shouf Area, Lebanon, PA, Lebanon.
Adv Exp Med Biol. 2017;996:193-205. doi: 10.1007/978-3-319-56017-5_16.
Type 2 diabetes mellitus (T2DM) has become a significant global health care problem and its reported incidence is increasing at an alarming rate. Despite the improvement in therapy and development of new drugs, treatment still remains insufficient especially due to the associated side effects of most available drugs. Efforts are continuing toward disease prevention and search for safer drugs. Conflicting evidence is associating low levels of vitamin D in the body to T2DM and as such studies have been conducted to test the effect of vitamin D levels on incidence of diabetes, diabetic control as well as diabetic complications.Despite the conflicting evidence, vitamin D replacement seems to have some beneficial effect on the many aspects of diabetes: incidence, control and complications. Further long term and more convincing controlled trials are required in order to draw firmer conclusions on this beneficial role of vitamin D treatment on T2DM.
2型糖尿病（T2DM）已成为一个重大的全球医疗保健问题，其报告发病率正以惊人的速度上升。尽管治疗有所改善且新药不断研发，但治疗仍显不足，尤其是由于大多数现有药物存在相关副作用。目前仍在努力进行疾病预防并寻找更安全的药物。有相互矛盾的证据表明体内维生素D水平低与T2DM有关，因此已开展研究来测试维生素D水平对糖尿病发病率、糖尿病控制以及糖尿病并发症的影响。尽管存在相互矛盾的证据，但维生素D替代疗法似乎在糖尿病的许多方面都有一些有益作用：发病率、控制和并发症。需要进一步进行长期且更有说服力的对照试验，以便就维生素D治疗对T2DM的这种有益作用得出更确凿的结论。
