a Active Carbohydrate Research Center, Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry , Chongqing Normal University , Chongqing , China.
Drug Deliv. 2017;24(sup1):108-113. doi: 10.1080/10717544.2017.1399305.
Chitosan and its derivatives as vehicles for drug delivery can achieve the purpose of sustained release and controlled release for drugs, improve the stability of drugs, and reduce adverse drug reactions. So, the bioavailability of drugs can be enhanced. Therefore, chitosan and its derivatives have become a hotspot in the field of drug delivery. Their characteristics as drug delivery vectors were introduced, the types and applications were summarized. The development direction of chitosan and its derivatives in this field was also forecasted.
壳聚糖及其衍生物作为药物载体可以实现药物的缓释和控释目的,提高药物的稳定性,降低药物的不良反应。因此,可以提高药物的生物利用度。因此,壳聚糖及其衍生物已成为药物输送领域的一个热点。介绍了其作为药物载体的特点,总结了其类型和应用。还预测了壳聚糖及其衍生物在该领域的发展方向。