Heideman M, Gelin L E
Acta Chir Scand Suppl. 1979;489:215-23.
Injury can activate the complement system as well in vivo as in vitro. This activation might contribute to some of the phenomena seen after large injuries. Such general effects as fall in blood pressure, impaired ability to oxygenate blood and local effects such as accumulation of granulocytes and oedema formation might be influenced by complement activity. The in vitro experiments indicated an alternative pathway activation of whole complement by injured tissue or endotoxin.
损伤在体内和体外均可激活补体系统。这种激活可能与严重损伤后出现的一些现象有关。诸如血压下降、血液氧合能力受损等全身性效应以及粒细胞聚集和水肿形成等局部效应可能会受到补体活性的影响。体外实验表明，受损组织或内毒素可通过替代途径激活整个补体系统。
