Suppr超能文献

小儿克罗恩病患者的外科治疗

Surgical care of the pediatric Crohn's disease patient.

作者信息

Stewart Dylan

机构信息

Department of Surgery, Johns Hopkins School of Medicine, Johns Hopkins Children's Center, 1800 Orleans St, Bloomberg Suite 7335, Baltimore, MD 21287.

出版信息

Semin Pediatr Surg. 2017 Dec;26(6):373-378. doi: 10.1053/j.sempedsurg.2017.10.007. Epub 2017 Oct 5.

Abstract

Despite the significant advances in the medical management of inflammatory bowel disease over the last decade, surgery continues to play a major role in the management of pediatric Crohn's disease (CD). While adult and pediatric Crohn's disease may share many clinical characteristics, pediatric Crohn's patients often have a more aggressive phenotype, and the operative care given by the pediatric surgeon to the newly diagnosed Crohn's patient is very different in nature to the surgical needs of adult patients after decades of disease progression. Children also have the unique surgical indication of growth failure to consider in the overall clinical decision making. While surgery is never curative in CD, it has the ability to transform the disease process in children, and appropriately timed operations may have tremendous impact on a child's physical and mental maturation. This monograph aims to address the surgical care of Crohn's disease in general, with a specific emphasis on the surgical treatment of small intestinal and ileocecal involvement.

摘要

尽管在过去十年中炎症性肠病的药物治疗取得了重大进展,但手术在小儿克罗恩病(CD)的治疗中仍起着重要作用。虽然成人和小儿克罗恩病可能有许多共同的临床特征,但小儿克罗恩病患者通常具有更具侵袭性的表型,小儿外科医生对新诊断的克罗恩病患者的手术治疗在本质上与成年患者经过数十年疾病进展后的手术需求有很大不同。在整体临床决策中,儿童还存在生长发育迟缓这一独特的手术指征需要考虑。虽然手术不能治愈克罗恩病,但它有能力改变儿童的疾病进程,适时的手术可能会对儿童的身心成熟产生巨大影响。本专著旨在总体上探讨克罗恩病的手术治疗,特别强调小肠和回盲部受累的手术治疗。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验