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克罗恩病的 Kono-S 吻合术:小儿患者的初步经验。

Kono-S anastomosis in Crohn's disease: initial experience in pediatric patients.

机构信息

Department of Paediatric Surgery, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, Praha 5, Czech Republic.

Department of Paediatrics, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

出版信息

Pediatr Surg Int. 2024 Mar 5;40(1):67. doi: 10.1007/s00383-024-05648-6.

DOI:10.1007/s00383-024-05648-6
PMID:38438752
Abstract

PURPOSE

Children diagnosed with Crohn's disease (CD) often undergo ileocecal resection (ICR) during childhood. Anastomotic recurrence is a frequent finding following this procedure. Data addressing the effect of the anastomosis type on disease recurrence are scarce in the pediatric population. The Kono-S anastomosis has shown promise in reducing endoscopic, clinical, and surgical recurrence rates in adults. We aimed to report our experience with Kono-S anastomosis in children, focusing on its feasibility and postoperative complications.

METHODS

We retrospectively analyzed pediatric CD patients who underwent ICR with Kono-S anastomosis between August 2022 and May 2023. Data on demographics, clinical characteristics, surgery, hospitalization, and follow-up including colonoscopy were collected. Complications were classified using the Clavien-Dindo classification.

RESULTS

Twelve patients (7 females, 58.3%) were included. Six (50%) of the patients had the B3 luminal form of the disease (according to Paris classification). Median surgery duration was 174 (interquartile range [IQR] 161-216) minutes. Anastomosis creation took a median of 62 (IQR, 54.5-71) minutes. Median hospitalization length was 6 (IQR 4-7) days. No short- or mid-term complications were observed. Median follow-up duration was 9.5 (IQR 6.8-12) months.

CONCLUSION

According to our results, Kono-S anastomosis is safe and feasible in pediatric CD patients, with no observed postoperative complications. These findings support the potential benefit of using Kono-S anastomosis as a treatment approach in children with CD.

摘要

目的

儿童克罗恩病(CD)患者常需接受回盲部切除术(ICR)。吻合口复发是该手术后的常见并发症。在儿科人群中,有关吻合方式对疾病复发影响的数据较为匮乏。Kono-S 吻合术在降低成人内镜、临床和手术复发率方面显示出良好的效果。我们旨在报告我们在儿童中应用 Kono-S 吻合术的经验,重点关注其可行性和术后并发症。

方法

我们回顾性分析了 2022 年 8 月至 2023 年 5 月期间接受 Kono-S 吻合术的儿童 CD 患者。收集了人口统计学、临床特征、手术、住院和随访(包括结肠镜检查)数据。并发症采用 Clavien-Dindo 分类进行分类。

结果

共纳入 12 例患者(7 例女性,58.3%)。其中 6 例(50%)患者的疾病存在 B3 腔外型(根据巴黎分类)。手术时间中位数为 174 分钟(四分位距 [IQR] 161-216)。吻合口建立时间中位数为 62 分钟(IQR 54.5-71)。中位住院时间为 6 天(IQR 4-7)。无近期或中期并发症。中位随访时间为 9.5 个月(IQR 6.8-12)。

结论

根据我们的结果,Kono-S 吻合术在儿童 CD 患者中是安全且可行的,术后无并发症发生。这些发现支持 Kono-S 吻合术作为儿童 CD 治疗方法的潜在益处。

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本文引用的文献

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Updates Surg. 2024 Jan;76(1):139-146. doi: 10.1007/s13304-023-01671-9. Epub 2023 Nov 9.
2
Children with Localized Crohn's Disease Benefit from Early Ileocecal Resection and Perioperative Anti-Tumor Necrosis Factor Therapy.局限性克罗恩病患儿从早期回盲部切除和围手术期抗肿瘤坏死因子治疗中获益。
Eur J Pediatr Surg. 2024 Jun;34(3):236-244. doi: 10.1055/s-0043-1764320. Epub 2023 Mar 16.
3
Complications and Disease Recurrence After Ileocecal Resection in Pediatric Crohn's Disease: A Retrospective Study.
小儿克罗恩病回肠末端切除术后的并发症和疾病复发:一项回顾性研究。
Eur J Pediatr Surg. 2024 Jun;34(3):253-260. doi: 10.1055/a-2048-7407. Epub 2023 Mar 7.
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Comparison of laparoscopic and open ileocecal resection for Crohn's disease in children.腹腔镜与开腹回肠结肠切除术治疗儿童克罗恩病的比较。
Pediatr Surg Int. 2023 Feb 27;39(1):140. doi: 10.1007/s00383-023-05419-9.
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