与呼吸机相关事件相比，合并感染相关呼吸机相关性并发症的烧伤患者预后更差。
Burn patients with infection-related ventilator associated complications have worse outcomes compared to those without ventilator associated events.
机构信息
Division of Acute Care Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, United States.
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States.
出版信息
Am J Surg. 2018 Apr;215(4):678-681. doi: 10.1016/j.amjsurg.2017.10.034. Epub 2017 Oct 31.
BACKGROUND
The Centers for Disease Control and Prevention (CDC) replaced its definition for ventilator-associated pneumonia (VAP) in 2013. The aim of the current study is to compare the outcome of burn patients with ventilator associated events (VAEs).
METHODS
Burn patients with at least two days of ventilator support were identified from the registry between 2013 and 2016. Kruskal-Wallis and Fisher's exact tests were utilized for continuous and categorical variables, respectively. A logistic regression was used for the association between VAE and in-hospital mortality.
RESULTS
243 patients were admitted to our burn center, of whom 208 had no VAE, 8 had a VAC, and 27 had an IVAC or PVAP. There was no difference in hospital length of stay, ICU length of stay and ventilator support days between those with no VAE and a VAC. Those with IVAC-plus had significantly worse outcomes compared to patients with no VAEs.
CONCLUSIONS
Burn patients with IVAC-plus had significantly longer hospital and ICU lengths of stay, days on ventilator compared with patients with no VAEs.
背景
疾病控制与预防中心（CDC）于 2013 年更新了呼吸机相关性肺炎（VAP）的定义。本研究旨在比较伴有呼吸机相关事件（VAEs）的烧伤患者的结局。
方法
从 2013 年至 2016 年的登记处中确定至少接受了两天呼吸机支持的烧伤患者。分别使用 Kruskal-Wallis 和 Fisher 确切检验对连续变量和分类变量进行分析。使用逻辑回归分析 VAE 与院内死亡率之间的关联。
结果
243 名患者被收入我们的烧伤中心，其中 208 例无 VAE，8 例有 VAC，27 例有 IVAC 或 PVAP。无 VAE 和 VAC 患者的住院时间、ICU 住院时间和呼吸机支持天数无差异。IVAC 附加组的患者与无 VAEs 的患者相比，预后明显更差。
结论
与无 VAEs 的患者相比，IVAC 附加组的烧伤患者的住院时间和 ICU 住院时间以及呼吸机支持天数明显更长。
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