MRC/UVRI Uganda Research Unit on AIDS, Plot 51-59 Nakiwogo Road, Entebbe, Uganda.
London School of Hygiene and Tropical Medicine, London, UK.
AIDS Behav. 2018 Mar;22(3):1053-1061. doi: 10.1007/s10461-017-1973-5.
Data on implementation of 'Test and Treat' among key populations in sub-Saharan Africa are still limited. We examined factors associated with prompt antiretroviral therapy/ART (within 1 month of HIV-positive diagnosis or 1 week if pregnant) among 343 women at high risk for HIV infection in Kampala-Uganda, of whom 28% initiated prompt ART. Most (95%) reported paid sex within 3 months prior to enrolment. Multivariable logistic regression was used to determine baseline characteristics associated with prompt ART. Sex work as main job, younger age and being widowed/separated were associated with lower odds of prompt ART; being enrolled after 12 months of implementing the intervention was associated with higher odds of prompt ART. Younger women, widowed/separated and those reporting sex work as their main job need targeted interventions to start ART promptly after testing. Staff supervision and mentoring may need strengthening during the first year of implementing 'test and treat' interventions.
撒哈拉以南非洲关键人群中“检测即治疗”的实施数据仍然有限。我们研究了乌干达坎帕拉的 343 名高危感染艾滋病毒的女性中，与及时接受抗逆转录病毒治疗/ART（HIV 阳性诊断后 1 个月内或怀孕后 1 周内）相关的因素，其中 28%的人及时开始了 ART。大多数（95%）人报告在入组前 3 个月内有偿性交易。采用多变量逻辑回归确定与及时 ART 相关的基线特征。以性工作为主要职业、年龄较小和丧偶/离异与及时 ART 的可能性较低相关；在实施干预措施 12 个月后入组与及时 ART 的可能性较高相关。年轻女性、丧偶/离异和报告性工作为主要职业的人需要有针对性的干预措施，以便在检测后及时开始接受 ART。在实施“检测即治疗”干预措施的第一年，可能需要加强工作人员监督和指导。
