Ničovský Jiří, Ondrášek Jiří, Černý Jan, Žáková Daniela, Němec Petr
Vnitr Lek. 2017 Fall;63(10):640-645.
The aortic root aneurysm is associated with a more frequent occurrence of aortic dissection and development of aortic regurgitation. The aim of this study was to compare outcomes of composite graft replacement and valve sparing root replacement in treating aortic root aneurysms.
From January 2006 to December 2015 a total of 137 patients (mean age 46.3 ± 14.5, range 16-65) underwent elective surgery for aortic root aneurysm without valvular structural defects. Replacement by mechanical composite graft (Bentall procedure) has been performed in 46 patients while 91 patients underwent valve sparing root replacement (David procedure). The mean length of follow-up has been 77 months.
There was no operative death. Overall 9 patients died during follow-up. Five patients were after Bentall procedure and 4 were after reimplantation of aortic valve. Thromboembolic and bleeding complications were observed in 7 patients, 5 of them were after Bentall surgery and 2 after reimplantation of the aortic valve. Five patients after reimplantation of aortic valve underwent reoperation. Four of these patients had aortic valve replacement and in 1 case aortic homograft was implanted.
Bentall procedure used to be the standard treatment for patients with aortic root aneurysms. During the past two decades, aortic valve sparing procedure has gained widespread use to reduce thromboembolic and bleeding complications.Key words: aortic root aneurysm - composite graft replacement - valve-sparing root replacement.
主动脉根部瘤与主动脉夹层更频繁的发生以及主动脉瓣关闭不全的发展相关。本研究的目的是比较复合移植物置换术和保留瓣膜的根部置换术治疗主动脉根部瘤的疗效。
2006年1月至2015年12月,共有137例患者(平均年龄46.3±14.5岁,范围16 - 65岁)接受了无瓣膜结构缺陷的主动脉根部瘤择期手术。46例患者采用机械复合移植物置换术(Bentall手术),91例患者接受保留瓣膜的根部置换术(David手术)。平均随访时间为77个月。
无手术死亡病例。随访期间共有9例患者死亡。5例在Bentall手术后死亡,4例在主动脉瓣再植入术后死亡。观察到7例血栓栓塞和出血并发症,其中5例在Bentall手术后,2例在主动脉瓣再植入术后。5例主动脉瓣再植入术后患者接受了再次手术。其中4例患者进行了主动脉瓣置换,1例植入了主动脉同种异体移植物。
Bentall手术曾是主动脉根部瘤患者的标准治疗方法。在过去二十年中,保留主动脉瓣手术已得到广泛应用,以减少血栓栓塞和出血并发症。关键词:主动脉根部瘤 - 复合移植物置换 - 保留瓣膜的根部置换