Department of Internal Medicine, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, C33H GH, Iowa City, IA 52242, USA.
Department of Internal Medicine, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, C33H GH, Iowa City, IA 52242, USA.
Clin Chest Med. 2017 Dec;38(4):761-770. doi: 10.1016/j.ccm.2017.07.011. Epub 2017 Sep 20.
Mycobacterial infections are uncommon in solid organ and hematopoietic stem cell transplant recipients but carry significant morbidity and mortality. Donor screening strategies for tuberculosis should be emphasized in high-risk populations. Both tuberculosis and nontuberculous mycobacterial infections can have pulmonary and extrapulmonary manifestations of infections. Recommended treatment regimens typically involve multiple drugs with significant adverse effects and drug interactions.
分枝杆菌感染在实体器官和造血干细胞移植受者中并不常见，但具有显著的发病率和死亡率。应在高危人群中强调针对结核病的供者筛查策略。结核分枝杆菌和非结核分枝杆菌感染均可有肺部和肺外感染表现。推荐的治疗方案通常涉及多种具有显著不良反应和药物相互作用的药物。
