实体器官及造血干细胞移植中的呼吸道病毒感染
Respiratory Viral Infections in Solid Organ and Hematopoietic Stem Cell Transplantation.
作者信息
Paulsen Grant C, Danziger-Isakov Lara
机构信息
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, S8.216 MLC 7017, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, S8.216 MLC 7017, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
出版信息
Clin Chest Med. 2017 Dec;38(4):707-726. doi: 10.1016/j.ccm.2017.07.012. Epub 2017 Sep 20.
Abstract
Respiratory viruses are common in solid organ and hematopoietic stem cell transplant recipients and a recognized cause of significant morbidity and mortality. Epidemiology, risk factors, and attributable mortality in both populations are reviewed. In addition, virus-specific prevention and treatment options, including emerging investigational therapies, are discussed for respiratory syncytial virus, influenza, adenovirus, parainfluenza, and other respiratory viruses.
摘要
呼吸道病毒在实体器官移植受者和造血干细胞移植受者中很常见，是导致严重发病和死亡的一个公认原因。本文综述了这两类人群中的流行病学、危险因素和可归因死亡率。此外，还讨论了针对呼吸道合胞病毒、流感病毒、腺病毒、副流感病毒和其他呼吸道病毒的病毒特异性预防和治疗方案，包括新兴的研究性疗法。
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