Leith Catherine P
Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, K4/434, 600 Highland Avenue, Madison, WI 53792, USA.
Clin Lab Med. 2017 Dec;37(4):915-929. doi: 10.1016/j.cll.2017.07.012. Epub 2017 Sep 28.
Cost-effective flow cytometry (FC) requires development of FC panels focused to common diagnoses and strategies to identify cases where limited FC testing is sufficient. Focused panels include sufficient antibodies and to identify common diseases and appropriate analysis strategies to identify rare diseases that need additional FC testing. Strategies to limit FC testing include the use of algorithms to predict disease probability, with limited FC performed if disease is unlikely. Successful algorithms use easily available parameters, have well-defined rules for use, and are periodically reviewed and updated to maximize efficiency while containing costs.
具有成本效益的流式细胞术（FC）需要开发针对常见诊断的FC检测板以及用于识别有限的FC检测就足够的病例的策略。针对性检测板包括足够的抗体，用于识别常见疾病，以及适当的分析策略，用于识别需要额外FC检测的罕见疾病。限制FC检测的策略包括使用算法来预测疾病概率，如果疾病可能性不大，则进行有限的FC检测。成功的算法使用易于获得的参数，具有明确的使用规则，并定期进行审查和更新，以在控制成本的同时最大限度地提高效率。
