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非骨水泥全膝关节置换术治疗膝关节骨坏死:至少三年的随访结果显示其具有优异的生存率和临床效果。

Cementless Total Knee Arthroplasty in Knee Osteonecrosis Demonstrated Excellent Survivorship and Outcomes at Three-Year Minimum Follow-Up.

机构信息

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.

Department of Orthopaedic Surgery, Mount Sinai West Hospital, New York, New York.

出版信息

J Arthroplasty. 2018 Mar;33(3):761-765. doi: 10.1016/j.arth.2017.10.018. Epub 2017 Nov 8.

Abstract

BACKGROUND

Lack of consensus exists on the use of cementless total knee arthroplasty (TKA) in patients with knee osteonecrosis. Therefore, this study was conducted to evaluate (1) implant survivorship; (2) clinical outcomes and complications; and (3) radiographic outcomes of primary cementless TKA in knee osteonecrosis.

METHODS

This study included 46 patients (49 knees) who had knee osteonecrosis and underwent primary cementless TKA and had a mean follow-up of 44 months (range 36-96). Kaplan-Meier analysis was used to evaluate implant survivorship. Follow-up was performed post-operatively at 6 weeks, 3 months, and annually thereafter. Clinical outcomes including the Knee Society Scores (KSS) for pain and function, changes in range-of-motion, complications, and radiographic outcomes were analyzed.

RESULTS

Aseptic implant survivorship was 97.9% (95% confidence interval 1.01-0.93) and all-cause implant survivorship was 95.9% (95% confidence interval 1.01-0.9), with 1 septic and 1 aseptic failures. The mean KSS for pain was 93 points (range 85-100) and the mean KSS for function was 84 points (range 70-90). Additionally, 1 patient had superficial wound necrosis and was treated with local wound care with no further sequela. Otherwise, no evidence of loosening, subsidence, or progressive radiolucencies were noted on radiological evaluation.

CONCLUSION

Excellent implant survivorship, clinical, and radiographic outcomes of primary cementless TKA in the setting of knee osteonecrosis was demonstrated. Although further long-term study is needed to validate survivorship, new generation cementless TKA implants provide promising results in this subset of patients.

摘要

背景

在膝关节骨坏死患者中使用非骨水泥全膝关节置换术(TKA)尚未达成共识。因此,本研究旨在评估(1)假体的存活率;(2)临床结果和并发症;以及(3)原发性非骨水泥 TKA 治疗膝关节骨坏死的影像学结果。

方法

本研究纳入了 46 例(49 膝)膝关节骨坏死患者,均行初次非骨水泥 TKA,平均随访 44 个月(36-96 个月)。采用 Kaplan-Meier 分析评估假体存活率。术后 6 周、3 个月及此后每年进行随访。分析临床结果(包括膝关节学会评分[KSS]的疼痛和功能评分、活动范围的变化、并发症和影像学结果)。

结果

无菌性假体存活率为 97.9%(95%置信区间 1.01-0.93),总假体存活率为 95.9%(95%置信区间 1.01-0.90),无菌性和感染性假体各 1 例失败。平均 KSS 疼痛评分为 93 分(85-100 分),平均 KSS 功能评分为 84 分(70-90 分)。此外,1 例患者发生浅表伤口坏死,经局部伤口护理治疗后无进一步后遗症。影像学评估未见假体松动、下沉或进行性透亮线。

结论

原发性非骨水泥 TKA 治疗膝关节骨坏死具有良好的假体存活率、临床和影像学结果。虽然需要进一步的长期研究来验证存活率,但新一代非骨水泥 TKA 假体在这组患者中提供了有前景的结果。

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