• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非骨水泥全膝关节置换术治疗膝关节骨坏死:至少三年的随访结果显示其具有优异的生存率和临床效果。

Cementless Total Knee Arthroplasty in Knee Osteonecrosis Demonstrated Excellent Survivorship and Outcomes at Three-Year Minimum Follow-Up.

机构信息

Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.

Department of Orthopaedic Surgery, Mount Sinai West Hospital, New York, New York.

出版信息

J Arthroplasty. 2018 Mar;33(3):761-765. doi: 10.1016/j.arth.2017.10.018. Epub 2017 Nov 8.

DOI:10.1016/j.arth.2017.10.018
PMID:29128233
Abstract

BACKGROUND

Lack of consensus exists on the use of cementless total knee arthroplasty (TKA) in patients with knee osteonecrosis. Therefore, this study was conducted to evaluate (1) implant survivorship; (2) clinical outcomes and complications; and (3) radiographic outcomes of primary cementless TKA in knee osteonecrosis.

METHODS

This study included 46 patients (49 knees) who had knee osteonecrosis and underwent primary cementless TKA and had a mean follow-up of 44 months (range 36-96). Kaplan-Meier analysis was used to evaluate implant survivorship. Follow-up was performed post-operatively at 6 weeks, 3 months, and annually thereafter. Clinical outcomes including the Knee Society Scores (KSS) for pain and function, changes in range-of-motion, complications, and radiographic outcomes were analyzed.

RESULTS

Aseptic implant survivorship was 97.9% (95% confidence interval 1.01-0.93) and all-cause implant survivorship was 95.9% (95% confidence interval 1.01-0.9), with 1 septic and 1 aseptic failures. The mean KSS for pain was 93 points (range 85-100) and the mean KSS for function was 84 points (range 70-90). Additionally, 1 patient had superficial wound necrosis and was treated with local wound care with no further sequela. Otherwise, no evidence of loosening, subsidence, or progressive radiolucencies were noted on radiological evaluation.

CONCLUSION

Excellent implant survivorship, clinical, and radiographic outcomes of primary cementless TKA in the setting of knee osteonecrosis was demonstrated. Although further long-term study is needed to validate survivorship, new generation cementless TKA implants provide promising results in this subset of patients.

摘要

背景

在膝关节骨坏死患者中使用非骨水泥全膝关节置换术(TKA)尚未达成共识。因此,本研究旨在评估(1)假体的存活率;(2)临床结果和并发症;以及(3)原发性非骨水泥 TKA 治疗膝关节骨坏死的影像学结果。

方法

本研究纳入了 46 例(49 膝)膝关节骨坏死患者,均行初次非骨水泥 TKA,平均随访 44 个月(36-96 个月)。采用 Kaplan-Meier 分析评估假体存活率。术后 6 周、3 个月及此后每年进行随访。分析临床结果(包括膝关节学会评分[KSS]的疼痛和功能评分、活动范围的变化、并发症和影像学结果)。

结果

无菌性假体存活率为 97.9%(95%置信区间 1.01-0.93),总假体存活率为 95.9%(95%置信区间 1.01-0.90),无菌性和感染性假体各 1 例失败。平均 KSS 疼痛评分为 93 分(85-100 分),平均 KSS 功能评分为 84 分(70-90 分)。此外,1 例患者发生浅表伤口坏死,经局部伤口护理治疗后无进一步后遗症。影像学评估未见假体松动、下沉或进行性透亮线。

结论

原发性非骨水泥 TKA 治疗膝关节骨坏死具有良好的假体存活率、临床和影像学结果。虽然需要进一步的长期研究来验证存活率,但新一代非骨水泥 TKA 假体在这组患者中提供了有前景的结果。

相似文献

1
Cementless Total Knee Arthroplasty in Knee Osteonecrosis Demonstrated Excellent Survivorship and Outcomes at Three-Year Minimum Follow-Up.非骨水泥全膝关节置换术治疗膝关节骨坏死:至少三年的随访结果显示其具有优异的生存率和临床效果。
J Arthroplasty. 2018 Mar;33(3):761-765. doi: 10.1016/j.arth.2017.10.018. Epub 2017 Nov 8.
2
Cementless 3D Printed Highly Porous Titanium-Coated Baseplate Total Knee Arthroplasty: Survivorship and Outcomes at 2-Year Minimum Follow-Up.无骨水泥3D打印高孔隙率钛涂层基板全膝关节置换术:至少2年随访的生存率和结果
J Knee Surg. 2020 Mar;33(3):279-283. doi: 10.1055/s-0039-1677842. Epub 2019 Feb 6.
3
Outcomes of Cementless Total Knee Arthroplasty in Patients With Rheumatoid Arthritis.类风湿关节炎患者非骨水泥型全膝关节置换术的疗效
Orthopedics. 2018 Mar 1;41(2):103-106. doi: 10.3928/01477447-20180123-05. Epub 2018 Jan 29.
4
Cementless Total Knee Arthroplasty in Patients Older Than 75 Years.75岁以上患者的非骨水泥全膝关节置换术
J Knee Surg. 2017 Nov;30(9):930-935. doi: 10.1055/s-0037-1599253. Epub 2017 Apr 11.
5
Outcomes of Newer Generation Cementless Total Knee Arthroplasty: Beaded Periapatite-Coated vs Highly Porous Titanium-Coated Implants.新一代非骨水泥全膝关节置换术的结果:带珠磷灰石涂层与高孔隙率钛涂层植入物的比较。
J Arthroplasty. 2017 Jul;32(7):2156-2160. doi: 10.1016/j.arth.2017.01.044. Epub 2017 Feb 3.
6
Satisfactory results at 8 years mean follow-up after ADVANCE® medial-pivot total knee arthroplasty.ADVANCE® 内侧旋转铰链全膝关节置换术后8年平均随访的满意结果。
Knee. 2014 Mar;21(2):387-90. doi: 10.1016/j.knee.2013.10.005. Epub 2013 Oct 23.
7
Short-to-Midterm Outcomes of Revision Total Knee Arthroplasty Patients With a Total Stabilizer Knee System.采用全稳定型膝关节系统的翻修全膝关节置换术患者的短期至中期结果
J Arthroplasty. 2017 Aug;32(8):2480-2483. doi: 10.1016/j.arth.2017.02.065. Epub 2017 Mar 2.
8
Total Knee Arthroplasty Using Cementless Porous Tantalum Monoblock Tibial Component: A Minimum 10-Year Follow-Up.使用非骨水泥型多孔钽单块胫骨组件的全膝关节置换术:至少10年随访
J Arthroplasty. 2016 Oct;31(10):2193-8. doi: 10.1016/j.arth.2016.03.057. Epub 2016 Apr 12.
9
Cementless Posteriorly Stabilized Total Knee Arthroplasty: Seven-Year Minimum Follow-Up Report.非骨水泥后置稳定型全膝关节置换术:七年最低随访报告。
J Arthroplasty. 2018 May;33(5):1399-1403. doi: 10.1016/j.arth.2017.11.020. Epub 2017 Nov 16.
10
Cementless Tritanium Baseplate Total Knee Arthroplasty: Survivorship and Outcomes at 5-Year Minimum Follow-Up.无骨三钛基臼垫板全膝关节置换术:5 年最低随访的生存率和结果。
J Knee Surg. 2020 Sep;33(9):862-865. doi: 10.1055/s-0040-1712983. Epub 2020 Jun 19.

引用本文的文献

1
Cementless total knee arthroplasty: Why, when, and how.非骨水泥全膝关节置换术:为何、何时以及如何进行。
J Clin Orthop Trauma. 2025 Apr 1;65:102993. doi: 10.1016/j.jcot.2025.102993. eCollection 2025 Jun.
2
Total Joint Arthroplasty Is a Viable Treatment Option for Patients With Osteonecrosis and Osteoarthritis After Bone Marrow Transplantation.全关节置换术是骨髓移植后患有骨坏死和骨关节炎患者的一种可行治疗选择。
Arthroplast Today. 2024 Apr 17;27:101373. doi: 10.1016/j.artd.2024.101373. eCollection 2024 Jun.
3
The Evolution, Current Indications and Outcomes of Cementless Total Knee Arthroplasty.
非骨水泥型全膝关节置换术的发展、当前适应证及疗效
J Clin Med. 2022 Nov 8;11(22):6608. doi: 10.3390/jcm11226608.
4
Clinical outcomes and survivorship of cementless triathlon total knee arthroplasties: a systematic review.非骨水泥型三联全膝关节置换术的临床疗效与生存率:一项系统评价
Arthroplasty. 2022 Jun 3;4(1):25. doi: 10.1186/s42836-022-00124-9.
5
Subchondral stem cell therapy versus contralateral total knee arthroplasty for osteoarthritis following secondary osteonecrosis of the knee.膝关节继发骨坏死性骨关节炎的软骨下干细胞治疗与对侧全膝关节置换术的比较
Int Orthop. 2018 Nov;42(11):2563-2571. doi: 10.1007/s00264-018-3916-9. Epub 2018 Mar 27.