Vaghjiani Raj G, Molena Daniela
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Chin Clin Oncol. 2017 Oct;6(5):47. doi: 10.21037/cco.2017.07.05.
Esophageal cancer (EC) is an aggressive malignancy associated with an overall poor prognosis. The specific risk factors for EC vary by histologic type as well as geographic distribution but there is no widely applicable screening strategy to date. Patients can present with vague symptoms which can prove to be a diagnostic challenge. Furthermore, cases tend to present at a late stage, making therapeutic approach difficult. Despite ongoing changes in management strategy, surgery remains the only viable option for cure in early stage malignancy. Advances in operative and peri-operative management have led to a relatively safe and efficacious procedure that provides durable therapy. Additionally, careful consideration of procedure specific factors can help maximize patient benefit. This review focuses on the surgical approaches to the management of EC and highlights select current trends and recent advances.
食管癌(EC)是一种侵袭性恶性肿瘤,总体预后较差。EC的具体危险因素因组织学类型和地理分布而异,但迄今为止尚无广泛适用的筛查策略。患者可能出现模糊症状,这可能构成诊断挑战。此外,病例往往在晚期出现,使得治疗方法变得困难。尽管管理策略不断变化,但手术仍然是早期恶性肿瘤唯一可行的治愈选择。手术和围手术期管理的进展已导致一种相对安全有效的手术,可提供持久治疗。此外,仔细考虑手术特定因素有助于使患者受益最大化。本综述重点关注EC管理的手术方法,并突出当前的一些趋势和最新进展。