Rosenman J, Sherouse G W, Fuchs H, Pizer S M, Skinner A L, Mosher C, Novins K, Tepper J E
Department of Radiation Oncology, University of North Carolina, Chapel Hill 27514.
Int J Radiat Oncol Biol Phys. 1989 Jan;16(1):263-9. doi: 10.1016/0360-3016(89)90041-2.
Good radiation treatment planning requires that the target volume be treated with a high and uniform dose of radiation while irradiating normal tissue as little as possible. Even if the merits of a given treatment plan are judged only on the appearance of isodose lines in one or a few planes it can sometimes be difficult for the experienced radiation oncologist to select the best of several alternative plans. If consideration is given to the entire spatial distribution of dose, however, the problem becomes far more difficult because of the enormous amount of data that must be evaluated. We believe that the lack of suitable methods to display these data has greatly contributed to the slow incorporation of 3D considerations into routine radiation treatment planning. In the past few years there have been great advances in both the theory of how to produce effective 3D displays and in the display hardware itself. In this paper we survey some of the methods used at the University of North Carolina, and show specific examples of how these displays can be used in radiation therapy treatment planning.
好的放射治疗计划要求在尽可能少地照射正常组织的同时,用高剂量且均匀的辐射来治疗靶区。即使仅根据一个或几个平面上的等剂量线外观来判断给定治疗计划的优点,经验丰富的放射肿瘤学家有时也难以从几个备选计划中选出最佳方案。然而,如果考虑剂量的整个空间分布,由于必须评估的大量数据,问题会变得更加困难。我们认为,缺乏合适的方法来展示这些数据极大地阻碍了三维考量在常规放射治疗计划中的缓慢融入。在过去几年里,在如何制作有效的三维显示的理论以及显示硬件本身方面都取得了巨大进展。在本文中,我们概述了北卡罗来纳大学使用的一些方法,并展示了这些显示如何用于放射治疗计划的具体示例。