Goulet J A, Bray T J, Timmerman L A, Benson D R, Bargar W L
Department of Orthopaedics, University of California at Davis, Sacramento 95817.
J Bone Joint Surg Am. 1989 Jan;71(1):3-8.
The cases of 175 consecutive patients who had intraoperative autologous transfusion during revision total hip arthroplasty, an elective operation on the spine, repair of trauma to the spine, or open reduction of a fracture of the acetabulum were reviewed to evaluate the applicability of this technique in orthopaedic operations. A separate group of forty-one consecutive patients who had open reduction of a fracture of the acetabulum or the spine before the introduction of the autotransfuser was reviewed and compared with the group that had autotransfusion. An autologous blood predeposit program was used for twenty-five of fifty-two patients who had a procedure on the hip and for fifty-one of fifty-five patients who had an elective procedure on the spine. The mean rate of red blood-cell salvage using the autotransfuser was 60 per cent over-all. The mean transfusion requirements were significantly less (p less than 0.001) in all groups of patients in whom the autotransfuser was used. Use of the autotransfuser reduced the mean requirement for banked blood in patients who had a fracture of the acetabulum from 3.8 to 2.3 units per patient, and significantly reduced the mean need for banked blood in individuals who had trauma to the spine from 2.7 to 1.8 units per patient (p less than 0.01). The use of prebanked autologous blood further reduced the mean requirement for homologous blood from 2.4 to 0.8 unit per patient in those who had revision total hip arthroplasty (p less than 0.005), and from 3.6 to 0.4 unit per patient in those who had an elective procedure on the spine (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
回顾了175例在翻修全髋关节置换术、择期脊柱手术、脊柱创伤修复术或髋臼骨折切开复位术中接受术中自体输血的连续患者的病例,以评估该技术在骨科手术中的适用性。回顾了一组单独的41例连续患者,他们在自体输血器引入之前接受了髋臼或脊柱骨折切开复位术,并与接受自体输血的组进行比较。52例接受髋关节手术的患者中有25例以及55例接受脊柱择期手术的患者中有51例采用了自体血预存方案。使用自体输血器的总体红细胞回收平均率为60%。在所有使用自体输血器的患者组中,平均输血需求量显著更低(p<0.001)。使用自体输血器使髋臼骨折患者的库存血平均需求量从每位患者3.8单位降至2.3单位,并使脊柱创伤患者的库存血平均需求量从每位患者2.7单位显著降至1.8单位(p<0.01)。使用预存自体血进一步使翻修全髋关节置换术患者的异体血平均需求量从每位患者2.4单位降至0.8单位(p<0.005),并使脊柱择期手术患者的异体血平均需求量从每位患者3.6单位降至0.4单位(p<0.01)。(摘要截短于250词)