Woolson S T, Marsh J S, Tanner J B
J Bone Joint Surg Am. 1987 Mar;69(3):325-8.
The efficacy of a program of transfusion of previously deposited autologous blood for patients undergoing total hip-replacement surgery was studied by comparing five different parameters for a group of fifty consecutive patients who deposited blood for autologous transfusion and a randomly chosen, closely matched control group of fifty patients who received only homologous blood. Sixty-two per cent of the patients in the group that deposited autologous blood did not receive additional homologous blood while in the hospital. The patients who deposited autologous blood had a mean preoperative hematocrit of 36 per cent, compared with 39 per cent for the control group, but the average postoperative hematocrits of the two groups did not differ (33 per cent). There was no significant difference in the average total loss of blood or need for replacement of blood between the groups. Transfusion-related complications developed in two patients in the control group. We concluded that previous deposit of autologous blood for transfusion is an effective method for reducing the need for transfusion of homologous blood and for avoiding the attendant complications of transfusion of homologous blood. This method of the replacement of blood should be considered for patients who are to undergo a major orthopaedic procedure on the hip.
通过比较连续50例储存自体血用于自体输血的患者和随机选取的、匹配良好的50例仅接受异体血输血的对照组患者的五个不同参数，研究了预先储存自体血输血方案对接受全髋关节置换手术患者的疗效。储存自体血的患者组中有62%在住院期间未接受额外的异体血输血。储存自体血的患者术前平均血细胞比容为36%，而对照组为39%，但两组术后平均血细胞比容无差异（均为33%）。两组之间的平均总失血量或输血需求无显著差异。对照组有两名患者出现了与输血相关的并发症。我们得出结论，预先储存自体血用于输血是一种有效的方法，可减少异体血输血需求，并避免异体血输血带来的相关并发症。对于即将接受髋关节重大骨科手术的患者，应考虑这种血液替代方法。
