Pediatric Research Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece.
Department of Hygiene, Epidemiology and Medical Statistics, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Biomed Res Int. 2017;2017:5242048. doi: 10.1155/2017/5242048. Epub 2017 Oct 10.
The increasing trend of administering nonprescribed medicines in children is a significant public health issue. The aim of the present study was to assess the use of medication without a prescription (MWP), including both nonprescribed medication (NPM) and prescription-only medication (POM), and identify associated factors, among preschoolers in Athens, Greece. A predesigned questionnaire was distributed to parents from May through June 2011. Multivariable binary logistic regression analysis models were used to assess associations of interest. Results showed that 95.1% of parents reported administering at least one MWP, during the previous 12 months. Antipyretics (91%) were the most commonly NPM and bronchodilators (24.8%) and antibiotics (16.4%) the most common POM dispensed. Child's increased age group, lack of parental information, higher paternal education, and mother's foreign nationality were associated with increased antipyretic use ( < 0.05), while father's foreign nationality and parental age were positive predictors of antibiotic administration ( < 0.05). The likelihood of consuming antipyretics and antibiotics significantly increased when information was provided by a pharmacist ( = 0.017 and = 0.054, resp.). Conclusively, most parents have administered at least one MWP, including antibiotics, to address symptoms of common childhood diseases, highlighting the need of information campaigns concerning the consequences of their improper use.
在儿童中使用非处方药物的趋势不断增加,这是一个重大的公共卫生问题。本研究的目的是评估在希腊雅典的学龄前儿童中,未经处方使用药物(MWP)的情况,包括非处方药物(NPM)和仅限处方药物(POM),并确定相关因素。2011 年 5 月至 6 月期间,向家长分发了一份预先设计的问卷。使用多变量二元逻辑回归分析模型来评估相关因素。结果显示,95.1%的家长报告在过去 12 个月中至少给孩子使用过一种 MWP。解热药(91%)是最常用的 NPM,支气管扩张剂(24.8%)和抗生素(16.4%)是最常用的 POM。儿童年龄组增加、缺乏父母信息、父亲教育程度较高和母亲为外国国籍与解热药使用增加有关(<0.05),而父亲的外国国籍和父母年龄是抗生素使用的正预测因子(<0.05)。当信息由药剂师提供时,服用解热药和抗生素的可能性显著增加(=0.017 和=0.054,分别)。总之,大多数家长至少给孩子使用过一种 MWP,包括抗生素,以缓解常见儿童疾病的症状,这突出表明需要开展有关其不当使用后果的宣传活动。