Casals-Vázquez Cristina, Suárez-Cadenas Ernesto, Estébanez Carvajal Francisca María, Aguilar Trujillo María Pilar, Jiménez Arcos María M, Vázquez Sáchez María Ángeles
Instituto de Nutrición y Tecnología de los Alimentos. Centro de Investigación Biomédica. Universidad de Granada..
Nutr Hosp. 2017 Oct 24;34(5):1198-1204. doi: 10.20960/nh.1070.
The term sarcopenia is defined as age-related loss of skeletal muscle mass and function, with a consequent impact on quality of life. However, there is a lack of studies examining the prevalence of sarcopenia in patients with type 2 diabetes mellitus (DM).
To analyze the prevalence of sarcopenia in patients over 65 years with type 2 DM and the influence of physical activity, diet, glycemic control, sex, age, and quality of life.
A total of 279 patients (155 females), aged 76.6 ± 6.27 years, participated in this study in order to analyze body circumferences (waist, hip, calf, and arm), body mass index, handgrip strength, physical activity level, nutritional status, quality of life, and glycemic control. The cut-off value for sarcopenia was defined as the body mass index lower than 9.2 or 7.4 kg/m2 for males and females, respectively.
In participants, the prevalence of sarcopenia was 8.33%. Moreover, the level of sarcopenia was negatively associated with quality of life (r = -0.130, p = 0.030), physical activity (r = -0.164, p = 0.006), nutritional status (r = -0.274, p < 0.001), and male sex (r = -0.137, p = 0.022); and positively associated with age (r = 0.183, p = 0.002).
The prevalence of sarcopenia in patients with type 2 DM is moderate, and it is related to relevant health factors, such as lower quality of life, lower physical exercise level, and increased malnutrition, especially in older adult males.
肌肉减少症的定义为与年龄相关的骨骼肌质量和功能丧失，进而影响生活质量。然而，缺乏关于2型糖尿病（DM）患者中肌肉减少症患病率的研究。
分析65岁以上2型糖尿病患者中肌肉减少症的患病率以及身体活动、饮食、血糖控制、性别、年龄和生活质量的影响。
共有279名患者（155名女性）参与本研究，年龄为76.6±6.27岁，以分析身体周长（腰围、臀围、小腿围和臂围）、体重指数、握力、身体活动水平、营养状况、生活质量和血糖控制。肌肉减少症的临界值分别定义为男性低于9.2kg/m²、女性低于7.4kg/m²。
参与者中肌肉减少症的患病率为8.33%。此外，肌肉减少症的程度与生活质量（r=-0.130，p=0.030）、身体活动（r=-0.164，p=0.）、营养状况（r=-0.274，p<0.001）和男性性别（r=-0.137，p=0.022）呈负相关；与年龄呈正相关（r=0.183，p=0.002）。
2型糖尿病患者中肌肉减少症的患病率为中等水平，并且与相关健康因素有关，如生活质量较低、体育锻炼水平较低和营养不良增加，尤其是在老年男性中。
