根据老年人肌少症欧洲工作组（EWGSOP）标准的改编版本，智利社区居住老年人的肌少症患病率

Prevalence of Sarcopenia in Community-Dwelling Chilean Elders According to an Adapted Version of the European Working Group on Sarcopenia in Older People (EWGSOP) Criteria.

作者信息

Lera L, Albala C, Sánchez H, Angel B, Hormazabal M J, Márquez C, Arroyo P

机构信息

Dr. Cecilia Albala, Public Health Nutrition Unit, Institute of Nutrition and Food Technology (INTA) - University of Chile, El Líbano 5524, Casilla 138-11, Santiago, Chile, E-mail:

出版信息

J Frailty Aging. 2017;6(1):12-17. doi: 10.14283/jfa.2016.117.

DOI:10.14283/jfa.2016.117

PMID:28244552

Abstract

BACKGROUND

Sarcopenia is the progressive loss of mass and skeletal muscle strength and has serious consequences on older people's health. The Chilean older population has a high life-expectancy, but the prevalence of functional dependence is also high.

OBJECTIVE

To determine the prevalence of sarcopenia in Chilean older adults and its relationship with age, gender, and body mass index (BMI).

DESIGN

Cross-sectional study.

SETTING

Community.

PARTICIPANTS

1,006 non-disabled, community-dwelling subjects aged 60 years or older living in Santiago.

MEASUREMENTS

Anthropometric measurements, handgrip strength, physical performance tests, and dual-energy-x-ray-absorptiometry (DXA) scan were performed. Sarcopenia was defined using the algorithm of the European Working Group on Sarcopenia in Older People (EWGSOP). Muscle mass was measured with DXA scan; skeletal muscle mass index (SMI) and hand dynamometry were defined with cut-off points obtained for the Chilean population. For a 3m walking speed we used the cut-off point of the EWGSOP definition. Nutritional status and obesity were defined according to World Health Organization standards. Association between sarcopenia and age, gender, BMI and lean/fat mass ratio was estimated by logistic regression models.

RESULTS

The prevalence of sarcopenia was 19.1% (95%CI: 16.8%-21.8%), similar in men and women. There was an increasing trend of sarcopenia by age group and a decreasing trend with nutritional status. After logistic regression, sarcopenia was positively associated with age (OR=1.10; 95%CI:1.06-1.15) and falls (OR=1.83; 95%CI:1.07-3.15) and negatively associated with overweight (OR=0.31; 95%CI:0.16-0.59), obesity (OR=0.02; 95%CI:0.004-0.11), lean mass/fat mass ratio (OR=0.69; 95%CI:0.48-0.9997), knee height (OR=0.78; 95%CI:0.68-0.89) and calf circumference (OR=0.87; 95%CI:0.77-0.97).

CONCLUSIONS

The total prevalence of sarcopenia was 19.1% increasing with age reaching 39.6% in people of 80 or more years of age. A negative association of sarcopenia with overweight, obesity and lean/fat mass ratio was observed. Although the high prevalence of obesity (35.9%), only 2% of obese people were sarcopenic.

摘要

背景

肌肉减少症是肌肉质量和力量的渐进性丧失，对老年人的健康有严重影响。智利老年人口预期寿命较高，但功能依赖的患病率也很高。

目的

确定智利老年人肌肉减少症的患病率及其与年龄、性别和体重指数（BMI）的关系。

设计

横断面研究。

地点

社区。

参与者

居住在圣地亚哥的1006名60岁及以上的非残疾社区居民。

测量

进行人体测量、握力测试、身体性能测试和双能X线吸收法（DXA）扫描。采用欧洲老年人肌肉减少症工作组（EWGSOP）的算法定义肌肉减少症。通过DXA扫描测量肌肉质量；根据智利人群获得的切点定义骨骼肌质量指数（SMI）和手握力。对于3米步行速度，我们采用EWGSOP定义的切点。根据世界卫生组织标准定义营养状况和肥胖。通过逻辑回归模型估计肌肉减少症与年龄、性别、BMI以及瘦/脂肪质量比之间的关联。

结果

肌肉减少症的患病率为19.1%（95%CI：16.8%-21.8%），男性和女性相似。按年龄组划分，肌肉减少症呈上升趋势，与营养状况呈下降趋势。逻辑回归后，肌肉减少症与年龄（OR=1.10；95%CI：1.06-1.15）和跌倒（OR=1.83；95%CI：1.07-3.15）呈正相关，与超重（OR=0.31；95%CI：0.16-0.59）、肥胖（OR=0.02；95%CI：0.004-0.11）、瘦质量/脂肪质量比（OR=0.69；95%CI：0.48-0.9997）、膝高（OR=0.78；95%CI：0.68-0.89）和小腿围（OR=0.87；95%CI：0.77-0.97）呈负相关。