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肠白塞病患者急诊就诊的风险因素和结局。

Risk Factors and Outcomes of Emergency Room Visits in Intestinal Behçet's Disease.

机构信息

Department of Internal Medicine, Seoul, Republic of Korea.

Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Digestion. 2017 Nov;96(4):231-238. doi: 10.1159/000484084. Epub 2017 Nov 2.

DOI:10.1159/000484084
PMID:29131059
Abstract

BACKGROUND/AIMS: Intestinal Behçet's disease (BD) is a chronic recurring intestinal vasculitic disorder that can lead to emergency room (ER) visits. We aimed to investigate the independent risk factors associated with intestinal BD-related ER visits.

METHODS

We retrospectively reviewed 606 patients with intestinal BD registered at the Inflammatory Bowel Disease Clinic of Severance Hospital, Seoul, Korea.

RESULTS

One hundred eighty-five patients (30.5%) visited the ER at least once (total visits, 510). In multivariate analysis, lower socioeconomic status (hazard ratio [HR] 1.884), higher comorbidity index (HR 1.548), corticosteroid use (HR 1.459), higher C-reactive protein (CRP; HR 1.375), and higher disease activity index for intestinal BD (DAIBD) score (HR 1.013) were independent risk factors. However, older age (HR 0.982), disease duration (HR 0.850), opioid use (HR 0.528), and higher hemoglobin level (HR 0.944) were significantly associated with decreased ER visits.

CONCLUSIONS

The ER attendance rate of patients with intestinal BD was 30.5%. Lower socioeconomic status, higher comorbidity index, corticosteroid use, higher CRP, and higher DAIBD score were positively associated with ER visits. Older age, disease duration, opioid use, and higher hemoglobin level were significantly associated with decreased ER visits.

摘要

背景/目的:肠型贝赫切特病(BD)是一种慢性反复发作的肠道血管炎性疾病,可导致患者前往急诊室(ER)就诊。我们旨在探讨与肠型 BD 相关的 ER 就诊相关的独立危险因素。

方法

我们回顾性分析了韩国首尔 Severance 医院炎症性肠病诊所登记的 606 例肠型 BD 患者。

结果

185 例患者(30.5%)至少一次(总就诊次数为 510 次)前往 ER。多因素分析显示,较低的社会经济地位(风险比 [HR] 1.884)、较高的合并症指数(HR 1.548)、皮质类固醇的使用(HR 1.459)、较高的 C 反应蛋白(HR 1.375)和较高的肠型 BD 疾病活动指数(DAIBD)评分(HR 1.013)是独立的危险因素。然而,年龄较大(HR 0.982)、疾病持续时间(HR 0.850)、阿片类药物的使用(HR 0.528)和较高的血红蛋白水平(HR 0.944)与 ER 就诊次数减少显著相关。

结论

肠型 BD 患者的 ER 就诊率为 30.5%。较低的社会经济地位、较高的合并症指数、皮质类固醇的使用、较高的 CRP 和较高的 DAIBD 评分与 ER 就诊呈正相关。年龄较大、疾病持续时间、阿片类药物的使用和较高的血红蛋白水平与 ER 就诊次数减少显著相关。

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