From the Departments of Radiology (C.L.V., C.P.V., A.C., D.D.C., J.M.H., P.N., F.H.M.), Pathology (T.J.D., G.Y.Y.), and Urology (D.T.O.), Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Suite 800, Chicago, IL 60611.
Radiographics. 2017 Nov-Dec;37(7):2026-2042. doi: 10.1148/rg.2017170039.
Characterization of renal tumors is critical to determine the best therapeutic approach and improve overall patient survival. Because of increased use of high-resolution cross-sectional imaging in clinical practice, renal masses are being discovered with increased frequency. As a result, accurate imaging characterization of these lesions is more important than ever. However, because of the wide array of imaging features encountered as well as overlapping characteristics, identifying reliable imaging criteria for differentiating malignant from benign renal masses remains a challenge. Multiparametric magnetic resonance (MR) imaging based on various anatomic and functional parameters has an important role and adds diagnostic value in detection and characterization of renal masses. MR imaging may allow distinction of benign solid renal masses from several renal cell carcinoma (RCC) subtypes, potentially suggest the histologic grade of a neoplasm, and play an important role in ensuring appropriate patient management to avoid unnecessary surgery or other interventions. It is also a useful noninvasive imaging tool for patients who undergo active surveillance of renal masses and for follow-up after treatment of a renal mass. The purpose of this article is to review the characteristic MR imaging features of RCC and common benign renal masses and propose a diagnostic imaging approach to evaluation of solid renal masses using multiparametric MR imaging. RSNA, 2017.
对肾肿瘤进行特征分析对确定最佳治疗方法和提高整体患者生存率至关重要。由于在临床实践中越来越多地使用高分辨率的横截面成像,因此越来越频繁地发现肾肿块。结果,这些病变的准确成像特征分析比以往任何时候都更加重要。然而,由于遇到的成像特征范围广泛且特征重叠,因此确定区分恶性和良性肾肿块的可靠成像标准仍然是一个挑战。基于各种解剖和功能参数的多参数磁共振(MR)成像在检测和特征分析肾肿块方面具有重要作用并增加了诊断价值。MR 成像可以区分良性实性肾肿块和几种肾细胞癌(RCC)亚型,可能提示肿瘤的组织学分级,并在确保适当的患者管理以避免不必要的手术或其他干预方面发挥重要作用。它也是对接受肾肿块主动监测和肾肿块治疗后随访的患者有用的非侵入性成像工具。本文的目的是回顾 RCC 和常见良性肾肿块的特征性 MR 成像特征,并提出一种使用多参数 MR 成像评估实性肾肿块的诊断成像方法。RSNA,2017 年。