Maynard Erin
Department of Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Surg Clin North Am. 2017 Dec;97(6):1419-1424. doi: 10.1016/j.suc.2017.07.010. Epub 2017 Oct 5.
The critically ill patient with decompensated cirrhosis has a unique physiology and alterations in albumin that need to be understood to properly resuscitate them and minimize morbidity and mortality. Little data exist on specific resuscitation of the patient with cirrhosis compared with those patients without liver disease. The effectiveness of albumin administration compared with saline administration in common settings, such as large-volume paracentesis, can be extrapolated to the care of the general surgical patient but further studies in this area are warranted. This article enhances the understanding of unique physiology of the patient with decompensated cirrhosis to guide their needs in fluid resuscitation in critical illness.
失代偿期肝硬化的重症患者具有独特的生理特征以及白蛋白的变化,需要对此加以了解,以便对他们进行恰当的复苏,并将发病率和死亡率降至最低。与无肝脏疾病的患者相比,关于肝硬化患者特异性复苏的资料很少。在诸如大量腹腔穿刺放液等常见情况下,白蛋白给药与生理盐水给药相比的有效性可外推至普通外科患者的护理,但该领域仍需进一步研究。本文增进了对失代偿期肝硬化患者独特生理特征的理解,以指导其在危重病中液体复苏的需求。