Ohri Nisha, Haffty Bruce G
Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08901, USA.
Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08901, USA.
Surg Oncol Clin N Am. 2018 Jan;27(1):181-194. doi: 10.1016/j.soc.2017.07.006.
Adjuvant whole-breast irradiation (WBI) after lumpectomy has been an established standard of care for decades. Standard-fractionation WBI delivered over 5 to 7 weeks can achieve durable tumor control with low toxicity but can be inconvenient for patients and cost ineffective. Hypofractionated WBI can be completed in 3 to 4 weeks and, based on long-term randomized data, is the preferred standard of care in select patients. Accelerated partial-breast irradiation can be delivered using even shorter treatment regimens. Although the available data on accelerated partial-breast irradiation is more limited, early results suggest it is an effective alternative to WBI in select patients.
乳房肿瘤切除术后辅助性全乳照射（WBI）数十年来一直是既定的护理标准。在5至7周内进行的标准分割WBI可实现持久的肿瘤控制，且毒性较低，但对患者来说可能不方便且成本效益不高。大分割WBI可在3至4周内完成，根据长期随机数据，它是特定患者首选的护理标准。加速部分乳腺照射可以采用更短的治疗方案。尽管关于加速部分乳腺照射的现有数据较为有限，但早期结果表明，在特定患者中，它是WBI的有效替代方案。
