Gallagher Kristalyn, Marulanda Kathleen, Gray Stephanie
Department of Surgery, The University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170 Manning Drive, Chapel Hill, NC 27599-7123, USA.
Department of Surgery, The University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170 Manning Drive, Chapel Hill, NC 27599-7123, USA.
Surg Oncol Clin N Am. 2018 Jan;27(1):195-215. doi: 10.1016/j.soc.2017.08.001.
Lymphedema is a chronic, progressive disease with no curative treatment. Breast cancer therapy is the most common cause of secondary lymphedema in the developed world. Treatment includes nonsurgical and surgical strategies. Conservative measures are reserved for subclinical lymphedema. Surgical options are divided into physiologic (to restore function) and reductive (to remove diseased tissue). Early stage disease is managed with physiologic procedures. Reductive treatment is reserved for moderate to severe staged disease owing to high morbidity. Surgical options effectively decrease edema and improve quality of life. However, further research is necessary to best establish management of lymphedema.
淋巴水肿是一种慢性、进行性疾病，尚无治愈性疗法。在发达国家，乳腺癌治疗是继发性淋巴水肿最常见的病因。治疗方法包括非手术和手术策略。保守措施适用于亚临床淋巴水肿。手术选择分为生理性（恢复功能）和减容性（切除病变组织）。早期疾病采用生理性手术治疗。由于发病率高，减容性治疗适用于中重度分期的疾病。手术选择可有效减轻水肿并改善生活质量。然而，有必要进行进一步研究以更好地确立淋巴水肿的管理方法。
