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嗜酸性食管炎的诊断与管理

Diagnosis and Management of Eosinophilic Esophagitis.

作者信息

Wilson Jeffrey M, McGowan Emily C

机构信息

Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA.

Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, 501 Hopkins Bayview Circle, Baltimore, MD 21224, USA.

出版信息

Immunol Allergy Clin North Am. 2018 Feb;38(1):125-139. doi: 10.1016/j.iac.2017.09.010. Epub 2017 Nov 6.

DOI:10.1016/j.iac.2017.09.010
PMID:29132668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5777515/
Abstract

Unlike traditional food allergies, immunoglobulin E (IgE) is not a key mediator of eosinophilic esophagitis (EoE). Nonetheless, foods antigens are important triggers of EoE, and allergists play an important role in management of this chronic disease. This review addresses insights into the diagnosis and management as it relates to our evolving understanding about the pathogenesis of EoE.

摘要

与传统食物过敏不同,免疫球蛋白E(IgE)并非嗜酸性食管炎(EoE)的关键介质。尽管如此,食物抗原仍是EoE的重要触发因素,过敏症专科医生在这种慢性病的管理中发挥着重要作用。本综述阐述了与我们对EoE发病机制不断演变的理解相关的诊断和管理见解。

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本文引用的文献

1
Diminishing Effectiveness of Long-Term Maintenance Topical Steroid Therapy in PPI Non-Responsive Eosinophilic Esophagitis.长期维持局部类固醇治疗对质子泵抑制剂无反应的嗜酸性粒细胞性食管炎的有效性降低
Clin Transl Gastroenterol. 2017 Jun 15;8(6):e97. doi: 10.1038/ctg.2017.27.
2
Efficacy of a 4-Food Elimination Diet for Children With Eosinophilic Esophagitis.四食物剔除饮食疗法对嗜酸细胞性食管炎患儿的疗效。
Clin Gastroenterol Hepatol. 2017 Nov;15(11):1698-1707.e7. doi: 10.1016/j.cgh.2017.05.048. Epub 2017 Jun 8.
3
Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults.嗜酸性食管炎指南:儿童和成人诊断与管理的循证声明及建议
United European Gastroenterol J. 2017 Apr;5(3):335-358. doi: 10.1177/2050640616689525. Epub 2017 Jan 23.
4
Retrospective Comparison of Fluticasone Propionate and Oral Viscous Budesonide in Children With Eosinophilic Esophagitis.丙酸氟替卡松与口服粘性布地奈德治疗嗜酸性食管炎患儿的回顾性比较
J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):26-32. doi: 10.1097/MPG.0000000000001626.
5
Association between atopic manifestations and eosinophilic esophagitis: A systematic review and meta-analysis.特应性表现与嗜酸性粒细胞性食管炎的关联:系统评价和荟萃分析。
Ann Allergy Asthma Immunol. 2017 May;118(5):582-590.e2. doi: 10.1016/j.anai.2017.02.006. Epub 2017 Mar 30.
6
Biologic Therapies for Immunoglobulin E-mediated Food Allergy and Eosinophilic Esophagitis.用于免疫球蛋白E介导的食物过敏和嗜酸性食管炎的生物疗法。
Immunol Allergy Clin North Am. 2017 May;37(2):369-396. doi: 10.1016/j.iac.2017.01.010.
7
Clinical Implications of Emerging Data on the Safety of Proton Pump Inhibitors.质子泵抑制剂安全性新数据的临床意义
Curr Treat Options Gastroenterol. 2017 Mar;15(1):1-9. doi: 10.1007/s11938-017-0115-5.
8
Eosinophilic esophagitis versus proton pump inhibitor-responsive esophageal eosinophilia: Transcriptome analysis.嗜酸性粒细胞性食管炎与质子泵抑制剂反应性食管嗜酸性粒细胞增多症:转录组分析
J Allergy Clin Immunol. 2017 Jun;139(6):2010-2013.e4. doi: 10.1016/j.jaci.2016.11.028. Epub 2017 Jan 4.
9
The Prevalence of Eosinophilic Esophagitis in Pediatric Patients with IgE-Mediated Food Allergy.IgE介导的食物过敏小儿患者中嗜酸性粒细胞性食管炎的患病率
J Allergy Clin Immunol Pract. 2017 Mar-Apr;5(2):369-375. doi: 10.1016/j.jaip.2016.11.020. Epub 2016 Dec 30.
10
Update on dietary therapy for eosinophilic esophagitis in children and adults.儿童和成人嗜酸性粒细胞性食管炎饮食疗法的最新进展。
Expert Rev Gastroenterol Hepatol. 2017 Feb;11(2):115-123. doi: 10.1080/17474124.2017.1271324. Epub 2016 Dec 23.