Wilson Jeffrey M, McGowan Emily C
Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA.
Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, 501 Hopkins Bayview Circle, Baltimore, MD 21224, USA.
Immunol Allergy Clin North Am. 2018 Feb;38(1):125-139. doi: 10.1016/j.iac.2017.09.010. Epub 2017 Nov 6.
Unlike traditional food allergies, immunoglobulin E (IgE) is not a key mediator of eosinophilic esophagitis (EoE). Nonetheless, foods antigens are important triggers of EoE, and allergists play an important role in management of this chronic disease. This review addresses insights into the diagnosis and management as it relates to our evolving understanding about the pathogenesis of EoE.
与传统食物过敏不同,免疫球蛋白E(IgE)并非嗜酸性食管炎(EoE)的关键介质。尽管如此,食物抗原仍是EoE的重要触发因素,过敏症专科医生在这种慢性病的管理中发挥着重要作用。本综述阐述了与我们对EoE发病机制不断演变的理解相关的诊断和管理见解。