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[塞内加尔达喀尔由镰刀菌属引起的趾间足癣]

[Interdigital tinea pedis resulting from Fusarium spp. in Dakar, Senegal].

作者信息

Diongue K, Diallo M A, Ndiaye M, Seck M C, Badiane A S, Ndiaye D

机构信息

Laboratoire de parasitologie-mycologie, CHU Aristide-Le-Dantec, BP 16477, Dakar, Sénégal; Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontologie, université Cheikh-Anta-Diop, BP 5005, Dakar, Sénégal.

Laboratoire de parasitologie-mycologie, CHU Aristide-Le-Dantec, BP 16477, Dakar, Sénégal.

出版信息

J Mycol Med. 2018 Mar;28(1):227-231. doi: 10.1016/j.mycmed.2017.10.005. Epub 2017 Nov 11.

Abstract

INTRODUCTION

Fungal interdigital tinea pedis (ITP) is a common pathology mainly due to dermatophytes and yeasts. Fusarium sp. is rarely incriminated in the genesis of intertrigo. In Dakar, a recent study conducted in 2016 on fungal ITP showed that Fusarium were more involved in the etiology of ITP than dermatophytes, coming just after yeasts dominated by Candida. Following this, we wanted to draw attention to the increasing incidence of ITP resulting from Fusarium spp., in Dakar, Senegal, and to analyze the epidemiological and mycological particularities of these ITP due to Fusarium spp.

PATIENTS AND METHODS

A retrospective study including all patients received at the laboratory for suspicion of ITP between January 1st, 2014 and June 30th, 2017 was conducted. Diagnosis was based on mycological examination, including direct examination and culture. Mycological analysis was considered positive when direct examination and culture were positive after at least one repeat.

RESULTS

Twenty-nine cases of Fusarium ITP accounting for 44.6% of all ITP in the study period were diagnosed in 15 men and 14 women. The mean age of the patients was 48.4 years. Fusarium ITP were diagnosed in immunocompetent patients except in two diabetics. The mean duration of the lesions was 6.83 years. The most frequent species isolated belonged to the Fusarium solani complex with 19 cases.

CONCLUSION

Fusarium ITP in a healthy subject requires regular monitoring because any subsequent decrease in immune defenses could lead to fatal hematogenous spread.

摘要

引言

真菌性足趾间足癣(ITP)是一种常见病症,主要由皮肤癣菌和酵母菌引起。镰刀菌很少被认为是擦烂的病因。在达喀尔,2016年对真菌性ITP进行的一项最新研究表明,镰刀菌在ITP病因中的作用比皮肤癣菌更大,仅次于以念珠菌为主的酵母菌。在此之后,我们希望引起人们对塞内加尔达喀尔由镰刀菌属引起的ITP发病率上升的关注,并分析这些由镰刀菌属引起的ITP的流行病学和真菌学特点。

患者与方法

进行了一项回顾性研究,纳入了2014年1月1日至2017年6月30日期间在实验室因疑似ITP而接受检查的所有患者。诊断基于真菌学检查,包括直接检查和培养。当直接检查和培养至少重复一次后均为阳性时,真菌学分析被认为是阳性。

结果

在研究期间诊断出29例镰刀菌性ITP,占所有ITP的44.6%,其中男性15例,女性14例。患者的平均年龄为48.4岁。除两名糖尿病患者外,镰刀菌性ITP在免疫功能正常的患者中被诊断出来。病变的平均持续时间为6.83年。分离出的最常见菌种属于茄病镰刀菌复合体,有19例。

结论

健康受试者中的镰刀菌性ITP需要定期监测,因为随后免疫防御功能的任何下降都可能导致致命的血行播散。

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