Diongue Khadim, Ndiaye Mouhamadou, Seck Mame Cheikh, Diallo Mamadou Alpha, Badiane Aïda Sadikh, Ndiaye Daouda
Laboratoire de Parasitologie-Mycology, CHU Le Dantec, BP 5005, Dakar, Senegal.
Service de Parasitologie-Mycology, Faculté de Médecine, de Pharmacie et d'Odontologie, Université Cheikh Anta Diop, BP 16477, Dakar, Senegal.
Dermatol Res Pract. 2017;2017:1268130. doi: 10.1155/2017/1268130. Epub 2017 Dec 4.
spp. represent 9 to 44% of onychomycoses caused by other than dermatophytes. This retrospective study describes 17 cases of onychomycosis diagnosed at the Laboratory of Parasitology and Mycology of Le Dantec University Hospital in Dakar, Senegal, from 2014 to 2016. It included all patients received in the laboratory for suspicion of onychomycosis between January 1, 2014, and December 31, 2016. Diagnosis was based on mycological examination including direct examination and culture. Mycological analysis was considered positive when direct examination and culture were positive after at least one repeat. Seventeen onychomycosis cases representing 12.9% of all onychomycoses reported were diagnosed. There were 5 cases on the fingernails and 12 on the toenails in 6 males and 11 females, and the mean age was 44 years (range: 26-64). Onychomycoses were diagnosed in immunocompetent patients except in a diabetic patient. The mean duration of lesions was 4.9 years (range: 1-15), and distal subungual onychomycosis was predominant. Almost all patients were from suburban areas of Dakar region. The most frequent species isolated belong to complex. Because of the risk of disseminated infection in immunocompromised patients, realization of susceptibility tests is necessary to ensure better therapeutic management.
spp.占非皮肤癣菌引起的甲真菌病的9%至44%。这项回顾性研究描述了2014年至2016年在塞内加尔达喀尔勒丹泰克大学医院寄生虫学和真菌学实验室诊断的17例甲真菌病病例。它包括2014年1月1日至2016年12月31日期间因疑似甲真菌病而在该实验室就诊的所有患者。诊断基于真菌学检查,包括直接检查和培养。当直接检查和培养在至少一次重复后呈阳性时,真菌学分析被认为是阳性的。确诊了17例甲真菌病病例,占报告的所有甲真菌病病例的12.9%。6名男性和11名女性中,有5例手指甲感染,12例脚趾甲感染,平均年龄为44岁(范围:26 - 64岁)。除一名糖尿病患者外,甲真菌病在免疫功能正常的患者中被诊断出来。病变的平均持续时间为4.9年(范围:1 - 15年),远端甲下甲真菌病最为常见。几乎所有患者都来自达喀尔地区的郊区。分离出的最常见菌种属于复合体。由于免疫功能低下患者有发生播散性感染的风险,进行药敏试验以确保更好的治疗管理是必要的。