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淋巴水肿:病理生理学和临床表现。

Lymphedema: Pathophysiology and clinical manifestations.

机构信息

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.

Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.

出版信息

J Am Acad Dermatol. 2017 Dec;77(6):1009-1020. doi: 10.1016/j.jaad.2017.03.022.

DOI:10.1016/j.jaad.2017.03.022
PMID:29132848
Abstract

Lymphedema is a localized form of tissue swelling resulting from excessive retention of lymphatic fluid in the interstitial compartment and caused by impaired lymphatic drainage. Lymphedema is classified as primary or secondary. Primary lymphedema is caused by developmental lymphatic vascular anomalies. Secondary lymphedema is acquired and arises as a result of an underlying systemic disease, trauma, or surgery. We performed PubMed and Google Scholar searches of the English-language literature (1966-2017) using the terms lymphedema, cancer-related lymphedema, and lymphatic complications. Relevant publications were manually reviewed for additional resources. This progressive chronic disease has serious implications on patients' quality of life. It is often misdiagnosed because it mimics other conditions of extremity swelling. There is no definitive cure for lymphedema. However, with proper diagnosis and management, its progression and potential complications may be limited.

摘要

淋巴水肿是一种组织肿胀的局部形式,是由于淋巴液在间质间隙中过度潴留以及淋巴引流受损引起的。淋巴水肿分为原发性和继发性。原发性淋巴水肿是由发育性淋巴管血管异常引起的。继发性淋巴水肿是获得性的,是由于潜在的系统性疾病、创伤或手术引起的。我们使用淋巴水肿、与癌症相关的淋巴水肿和淋巴并发症等术语,对 1966 年至 2017 年的英文文献进行了 PubMed 和 Google Scholar 搜索,并对相关出版物进行了人工审查,以获取更多资源。这种进行性慢性疾病严重影响患者的生活质量。由于它类似于其他肢体肿胀的情况,因此常常被误诊。目前还没有针对淋巴水肿的明确治愈方法。然而,通过正确的诊断和管理,可以限制其进展和潜在并发症。

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