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水稳定含铜金属有机框架材料的抗真菌活性

Antifungal activity of water-stable copper-containing metal-organic frameworks.

作者信息

Bouson Supaporn, Krittayavathananon Atiweena, Phattharasupakun Nutthaphon, Siwayaprahm Patcharaporn, Sawangphruk Montree

机构信息

Department of Microbiology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.

Department of Chemical and Biomolecular Engineering, School of Energy Science and Technology, Vidyasirimedhi Institute of Science and Technology, Rayong 21210, Thailand.

出版信息

R Soc Open Sci. 2017 Oct 11;4(10):170654. doi: 10.1098/rsos.170654. eCollection 2017 Oct.

DOI:10.1098/rsos.170654
PMID:29134075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5666258/
Abstract

Although metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially interesting, is investigated against , , and . The Cu-BTC MOF can effectively inhibit the growth rate of and remarkably inhibit the spore growth of , and . This finding shows the potential of using Cu-BTC MOF as a strong biocidal material against representative yeasts and moulds that are commonly found in the food and agricultural industries.

摘要

尽管金属有机框架材料（MOFs）或多孔配位聚合物已得到广泛研究，但其抗菌活性尚未得到充分研究。在本工作中，研究了具有水稳定性且具有工业应用价值的铜基苯三甲酸MOF（Cu-BTC MOF）对[此处原文缺失具体菌种名称]、[此处原文缺失具体菌种名称]、[此处原文缺失具体菌种名称]和[此处原文缺失具体菌种名称]的抗真菌活性。Cu-BTC MOF能有效抑制[此处原文缺失具体菌种名称]的生长速率，并显著抑制[此处原文缺失具体菌种名称]、[此处原文缺失具体菌种名称]和[此处原文缺失具体菌种名称]的孢子生长。这一发现表明，Cu-BTC MOF有潜力作为一种强大的杀菌材料，用于对抗食品和农业行业中常见的代表性酵母和霉菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/263250c3c555/rsos170654-g8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/e52eb32acf9c/rsos170654-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/c0e3283b6780/rsos170654-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/abb3768ce3aa/rsos170654-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/fa5cf450279a/rsos170654-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/d980cabfc7c4/rsos170654-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/27db4a9270c0/rsos170654-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/b4e3cc66986a/rsos170654-g7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/263250c3c555/rsos170654-g8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/e52eb32acf9c/rsos170654-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/c0e3283b6780/rsos170654-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/abb3768ce3aa/rsos170654-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/fa5cf450279a/rsos170654-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/d980cabfc7c4/rsos170654-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/27db4a9270c0/rsos170654-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/b4e3cc66986a/rsos170654-g7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3029/5666258/263250c3c555/rsos170654-g8.jpg

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