Jelavić S, Tobler D J, Hassenkam T, De Yoreo J J, Stipp S L S, Sand K K
Nano-Science Center, Department of Chemistry, University of Copenhagen, Universitetsparken 5, Copenhagen OE 2100, Denmark.
Chem Commun (Camb). 2017 Nov 23;53(94):12700-12703. doi: 10.1039/c7cc04276k.
We measured the binding energy and bonding parameters between model nucleotide functional groups and model clay mineral surfaces in solutions of acidic pH. We demonstrate that basal surfaces of clay minerals interact most strongly with nucleobases and show that the adsorption of the phosphate group to clay edges could facilitate polymerisation. Our results suggest that Al- and Fe-rich edge sites behave similarly in nucleotide polymerisation through change of the phosphodiester bond strength. We present an internally consistent set of thermodynamic parameters that represent the nucleotide-clay mineral system.
我们测量了酸性pH值溶液中模型核苷酸官能团与模型粘土矿物表面之间的结合能和键合参数。我们证明粘土矿物的基面与核碱基相互作用最强，并表明磷酸基团在粘土边缘的吸附可以促进聚合反应。我们的结果表明，富铝和富铁的边缘位点在核苷酸聚合过程中通过改变磷酸二酯键强度表现出相似的行为。我们给出了一组代表核苷酸 - 粘土矿物体系的内部一致的热力学参数。
