Ly Angelica, Yapp Michael, Nivison-Smith Lisa, Assaad Nagi, Hennessy Michael, Kalloniatis Michael
Centre for Eye Health, Sydney, New South Wales, Australia.
School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia.
Clin Exp Optom. 2018 Mar;101(2):172-181. doi: 10.1111/cxo.12624. Epub 2017 Nov 14.
Age-related macular degeneration is a common, complex and blinding eye disease. When early and intermediate levels of severity are detected in one or both eyes, there is a wide-ranging 0.4 to 53 per cent risk of progression to advanced disease in five years. In order to maximise visual outcomes for their patients, practising eye-care professionals must be able to stratify patients according to their risk of progression, intervene (for example by recommending smoking cessation or nutritional supplements and Amsler grid self-monitoring in intermediate disease) and monitor accordingly. With the aid of ocular imaging, a range of under-recognised yet meaningful risk factors have been identified. The purpose of this review is to assist the eye-care practitioner in stratifying the risk of progression in intermediate age-related macular degeneration using the range of established and emerging precursory signs that herald loss of vision.
年龄相关性黄斑变性是一种常见、复杂且致盲的眼病。当一只或两只眼睛检测到早期和中期严重程度时，五年内进展为晚期疾病的风险范围很广，为0.4%至53%。为了使患者的视觉效果最大化，执业眼科护理专业人员必须能够根据患者的进展风险对其进行分层，进行干预（例如，在中期疾病中建议戒烟、补充营养以及进行阿姆斯勒方格自我监测）并相应地进行监测。借助眼部成像，已经确定了一系列未被充分认识但有意义的风险因素。本综述的目的是帮助眼科护理从业者利用一系列预示视力丧失的既定和新出现的先兆体征，对中期年龄相关性黄斑变性的进展风险进行分层。
