Univ. Lille, CNRS, Central Lille, ISEN, Univ. Valenciennes, UMR 8520, IEMN, F-59000 Lille, France; Laboratoire de Nanomédecine, imagerie et thérapeutique, EA 4662, Université de Franche-Comté, 16 Route de Gray, 25030 Besançon, France; Centre for Development of Advanced Technologies (CDTA), Baba Hassen, Algeria; Semiconductors and Functional Materials Laboratory, University of Laghouat, Algeria.
Univ. Lille, CNRS, Central Lille, ISEN, Univ. Valenciennes, UMR 8520, IEMN, F-59000 Lille, France.
Talanta. 2018 Feb 1;178:432-440. doi: 10.1016/j.talanta.2017.09.065. Epub 2017 Sep 25.
Microsystems play an important role in many biological and environmental applications. The integration of electrical interfaces into such miniaturized systems provides new opportunities for electrochemical sensing where high sensitivity and selectivity towards the analyte are requested. This can be only achieved upon controlled functionalization of the working electrode, a challenge for compact microsystems. In this work, we demonstrate the benefit of electrophoretic deposition (EPD) of reduced graphene oxide/polyethylenimine (rGO/PEI) for the selective modification of a gold (Au) microelectrode in a microsystem comprising a Pt counter and a Ag/AgCl reference electrode. The functionalized microsystem was successfully applied for the sensing of dopamine with a detection limit of 50nM. Additionally, the microsystem exhibited good performance for the detection of dopamine levels in meat samples.
微系统在许多生物和环境应用中发挥着重要作用。将电气接口集成到这种微型系统中，为电化学传感提供了新的机会，因为需要对分析物具有高灵敏度和选择性。这只有在对工作电极进行受控功能化的情况下才能实现，这对于紧凑型微系统来说是一个挑战。在这项工作中，我们证明了电泳沉积 (EPD) 还原氧化石墨烯/聚乙烯亚胺 (rGO/PEI) 在选择性修饰金 (Au) 微电极方面的益处，该微电极位于包含铂对电极和银/氯化银参比电极的微系统中。功能化的微系统成功地用于检测多巴胺，检测限为 50nM。此外，该微系统在检测肉样中的多巴胺水平方面表现出良好的性能。
