Liu Fei, Wang Lei, Pang Shuang, Kan Quancheng
Department of Stomatology Department of Stomatology, School of Stomatoloy, Xinxiang Medical Collage, Xinxiang Department of Stomatology, Nanyang Stomatology Hospital, Nanyang Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Medicine (Baltimore). 2017 Nov;96(45):e8270. doi: 10.1097/MD.0000000000008270.
Our goal was to evaluate the risk factors for regional recurrence in upper lip squamous cell carcinoma (SCC).A total of 109 patients with upper lip SCC were retrospectively enrolled. Clinical and pathologic information was collected and analyzed.Fifteen (13.8%) patients had a regional metastasis, 2 patients had parotid node metastasis, and no local or distant metastasis was noted. There was neck level I node metastasis in 15 (100%) patients. In multivariate analysis, invasion depth and degree of differentiation were significantly associated with regional metastasis. The 5- and 10-year disease-specific survival rate was 95.4% and 80.1%, respectively.Invasion depth and degree of differentiation have reliable value for predicting regional metastasis.
我们的目标是评估上唇鳞状细胞癌（SCC）区域复发的危险因素。总共回顾性纳入了109例上唇SCC患者。收集并分析了临床和病理信息。15例（13.8%）患者发生区域转移，2例患者有腮腺淋巴结转移，未发现局部或远处转移。15例（100%）患者存在Ⅰ区颈部淋巴结转移。多因素分析显示，浸润深度和分化程度与区域转移显著相关。5年和10年疾病特异性生存率分别为95.4%和88.1%。浸润深度和分化程度对预测区域转移具有可靠价值。
