腮腺腺样囊性癌所致加辛综合征：一例报告
Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report.
作者信息
Xia Nian-Ge, Chen Yan-Yan, Wang Xin-Shi, Xu Hui-Qin, Zheng Rong-Yuan
机构信息
Department of Neurology, the First Affiliate Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang, P.R. China.
出版信息
Medicine (Baltimore). 2017 Nov;96(45):e8508. doi: 10.1097/MD.0000000000008508.
RATIONALE
Garcin syndrome is characterized by the gradual involvement, and ultimately, unilateral paralysis of at least 7 and sometimes all cranial nerves, without intracranial hypertension or any long tract signs.
PATIENT CONCERNS
We report the case of a 59-year-old woman who presented with Garcin syndrome, which gradually progressed over a period of 2 years.
DIAGNOSIS
A left parotid gland biopsy revealed parotid gland adenoid cystic carcinoma (PGACC) with perineural invasion of a peripheral nerve bundle and lymph node metastasis.
INTERVENTIONS
The patient was treated 3 times with local-field palliative radiotherapy.
OUTCOMES
She died after several months.
LESSONS
To the best of our knowledge, this is the first report of PGACC presenting as Garcin syndrome. PGACC is a rare tumor with a high propensity for perineural spread, and it should be considered as a possible cause of Garcin syndrome.
理论依据
加欣综合征的特点是至少7对颅神经逐渐受累，最终出现单侧麻痹，有时所有颅神经均受累，且无颅内高压或任何长束征。
患者情况
我们报告了一例59岁女性患者，患有加欣综合征，该综合征在2年时间里逐渐进展。
诊断
左侧腮腺活检显示为腮腺腺样囊性癌（PGACC），伴有外周神经束的神经周围浸润和淋巴结转移。
干预措施
患者接受了3次局部姑息性放疗。
结果
几个月后患者死亡。
经验教训
据我们所知，这是首例表现为加欣综合征的PGACC报告。PGACC是一种罕见肿瘤，具有较高的神经周围扩散倾向，应被视为加欣综合征的可能病因。
Zotero 插件