Fujii Masanori, Kiura Katsuyuki, Takigawa Nagio, Yumoto Tetsuya, Sehara Yoshihide, Tabata Masahiro, Tanimoto Mitsune
Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
J Thorac Oncol. 2007 Sep;2(9):877-8. doi: 10.1097/JTO.0b013e31811f473d.
Garcin syndrome consists of unilateral palsies of almost all cranial nerves without either sensory or motor long-tract disturbances and without intracranial hypertension, and it is caused by a malignant osteoclastic lesion at the skull base. A 60-year-old woman presented with dizziness and left facial palsy. Progressive left cranial nerve palsies developed over 2 months until gadolinium-enhanced magnetic resonance imaging of the brain revealed an intracranial extension of a tumor from the left skull base. A systemic survey revealed adenocarcinoma of the lung, which had metastasized along the skull base. We experienced a rare case of Garcin syndrome due to skull base metastases from lung cancer.
加欣综合征表现为几乎所有颅神经的单侧麻痹，无感觉或运动长束障碍，也无颅内高压，它由颅底的恶性破骨细胞性病变引起。一名60岁女性出现头晕和左侧面瘫。在2个月内逐渐出现左侧颅神经麻痹，直至脑部钆增强磁共振成像显示肿瘤从左侧颅底向颅内扩展。全身检查发现肺癌，已沿颅底转移。我们遇到了一例因肺癌颅底转移导致的罕见加欣综合征病例。
