Sjoberg R J, Blue P W, Kidd G S
Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado 80045-5001.
Am J Med Sci. 1989 Jan;297(1):42-5. doi: 10.1097/00000441-198901000-00010.
Although thyroidal uptake of gallium-67 has been described in several thyroid disorders, gallium-67 scanning is not commonly used in the evaluation of thyroid disease. Thyroidal gallium-67 uptake has been reported to occur frequently with subacute thyroiditis, anaplastic thyroid carcinoma, and thyroid lymphoma, and occasionally with Hashimoto's thyroiditis and follicular thyroid carcinoma. A patient is described with progressive systemic sclerosis who, while being scanned for possible active pulmonary involvement, was found incidentally to have abnormal gallium-67 uptake only in the thyroid gland. Fine needle aspiration cytology of the thyroid revealed Hashimoto's thyroiditis. Although Hashimoto's thyroiditis occurs with increased frequency in patients with progressive systemic sclerosis, thyroidal uptake of gallium-67 associated with progressive systemic sclerosis has not, to our knowledge, been previously described. Since aggressive thyroid malignancies frequently are imaged by gallium-67 scintigraphy, fine needle aspiration cytology of the thyroid often is essential in the evaluation of thyroidal gallium-67 uptake.
尽管在多种甲状腺疾病中都有关于甲状腺摄取镓-67的描述，但镓-67扫描在甲状腺疾病评估中并不常用。据报道，亚急性甲状腺炎、未分化甲状腺癌和甲状腺淋巴瘤中甲状腺摄取镓-67的情况较为常见，而桥本甲状腺炎和滤泡状甲状腺癌则偶尔出现这种情况。本文描述了一名患有进行性系统性硬化症的患者，在对其进行可能的活动性肺部受累扫描时，偶然发现仅甲状腺有异常的镓-67摄取。甲状腺细针穿刺细胞学检查显示为桥本甲状腺炎。尽管桥本甲状腺炎在进行性系统性硬化症患者中的发生率较高，但据我们所知，此前尚未描述过与进行性系统性硬化症相关的甲状腺摄取镓-67的情况。由于侵袭性甲状腺恶性肿瘤通常可通过镓-67闪烁扫描成像，因此在评估甲状腺镓-67摄取时，甲状腺细针穿刺细胞学检查往往至关重要。
