Huang T C, Lee D A
Jules Stein Eye Institute, Department of Ophthalmology, University of California, Los Angeles 90024-1771.
Am J Ophthalmol. 1989 Feb 15;107(2):151-5. doi: 10.1016/0002-9394(89)90214-6.
We studied the effects of punctal occlusion on the intraocular pressures of patients treated with topical medications for glaucoma. Silicone punctal plugs were used to occlude the inferior punctum of one eye in each of 19 patients treated with identical antiglaucoma eyedrops in both eyes. The intraocular pressures before and after punctal occlusion were compared. The eyes with the punctal plugs showed a statistically significant (P less than .0001) decrease in pressure of 1.32 mm Hg after punctal occlusion when compared to that of the fellow control unplugged eyes. The intraocular pressures in the plugged eyes decreased an average of 1.82 mm Hg after punctal occlusion when compared to before punctal occlusion (P = .001). The intraocular pressure in the unplugged control eyes did not change significantly after punctal occlusion of the fellow treated eye.
我们研究了泪点闭塞对使用局部药物治疗青光眼患者眼压的影响。在19例双眼均使用相同抗青光眼眼药水治疗的患者中，使用硅胶泪点塞阻塞每只眼睛的下泪点。比较泪点闭塞前后的眼压。与未植入泪点塞的对侧对照眼相比，植入泪点塞的眼睛在泪点闭塞后眼压显著降低（P小于0.0001），降低了1.32 mmHg。与泪点闭塞前相比，植入泪点塞的眼睛在泪点闭塞后眼压平均降低了1.82 mmHg（P = 0.001）。对侧治疗眼进行泪点闭塞后，未植入泪点塞的对照眼眼压无明显变化。
