Ingram D M, House A K, Garcia-Webb P
Aust N Z J Surg. 1979 Aug;49(4):466-9. doi: 10.1111/j.1445-2197.1979.tb05841.x.
Forty patients who underwent biliary surgery were investigated for postoperative pancreatic disturbance as measured by the amylase creatinine clearance ration (ACCR). Its relevance to preoperative pancreatitis, exploration of the common bile duct, and operative cholangiography were examined. The results suggested that a recent clinically proven episode of pancreatitis did not predispose to a postoperative recurrence following biliary surgery. Similarly, cholecystectomy alone did not produce a postoperative pancreatic disturbance. However, exploration of the common bile duct did frequently cause a postoperative elevated ACCR, and hence we recommend that duct exploration should be performed as carefully and as atraumatically as possible. The small number of patients who did not have operative cholangiograms prevented statistical evaluation of the effect of this procedure on the pancreas. However, information from elsewhere suggests that the plasma amylase level is not likely to be raised by cholangiography.
对40例行胆道手术的患者进行了术后胰腺功能紊乱的调查，通过淀粉酶肌酐清除率（ACCR）来衡量。研究了其与术前胰腺炎、胆总管探查及术中胆管造影的相关性。结果表明，近期经临床证实的胰腺炎发作并不易导致胆道手术后胰腺炎复发。同样，单纯胆囊切除术不会引起术后胰腺功能紊乱。然而，胆总管探查确实经常导致术后ACCR升高，因此我们建议胆总管探查应尽可能小心、无创地进行。未进行术中胆管造影的患者数量较少，无法对该操作对胰腺的影响进行统计学评估。然而，其他地方的信息表明，胆管造影不太可能使血浆淀粉酶水平升高。
