Donaldson L A, McIntosh W, Joffe S N
Gut. 1977 Jan;18(1):16-8. doi: 10.1136/gut.18.1.16.
The amylase creatinine clearance ratio (ACCR) is considered to be a more sensitive index of acute pancreatitis than the serum amylase level. Serial ACCR estimations were undertaken in 25 patients undergoing an elective cholecystectomy. Using accepted criteria, 28% of these patients developed, in the postoperative period, biochemical evidence of pancreatic gland damage, although the serum amylase level remained normal. This raised ACCR was particularly noted in patients who had undergone an exploration of the common bile duct. The ACCR would appear to be a more sensitive index of pancreatic gland disruption secondary to biliary surgery than the serum amylase level.
淀粉酶肌酐清除率（ACCR）被认为是比血清淀粉酶水平更敏感的急性胰腺炎指标。对25例行择期胆囊切除术的患者进行了连续ACCR测定。根据公认标准，这些患者中有28%在术后出现胰腺损伤的生化证据，尽管血清淀粉酶水平仍正常。这种升高的ACCR在接受胆总管探查的患者中尤为明显。ACCR似乎是比血清淀粉酶水平更敏感的胆道手术后胰腺破坏指标。
