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反常睡眠剥夺不影响大鼠海马体中的神经元兴奋性。

Paradoxical sleep deprivation does not affect neuronal excitability in the rat hippocampus.

作者信息

Gorter J A, Kamphuis W, Coenen A M

机构信息

Department of Comparative and Physiological Psychology, University of Nijmegen, The Netherlands.

出版信息

Brain Res. 1989 Jan 2;476(1):16-20. doi: 10.1016/0006-8993(89)91531-x.

DOI:10.1016/0006-8993(89)91531-x
PMID:2914211
Abstract

Before, during and after paradoxical sleep deprivation, field potentials, evoked in the CA1 region and in the fascia dentata of the hippocampus by means of paired pulse stimulation, were measured. Paradoxical sleep deprivation was applied for 3 days, using the platform and the pendulum technique. No changes were observed on evoked field potential amplitude, population spike or paired pulse depression during and after the deprivation period. These results suggest that the neuronal excitability in the rat hippocampus, measured with the evoked potential technique, does not change as a result of paradoxical sleep deprivation.

摘要

在反常睡眠剥夺之前、期间和之后,通过配对脉冲刺激测量海马体CA1区和齿状回诱发的场电位。使用平台和钟摆技术进行3天的反常睡眠剥夺。在剥夺期期间和之后,未观察到诱发场电位幅度、群体锋电位或配对脉冲抑制的变化。这些结果表明,用诱发电位技术测量的大鼠海马体神经元兴奋性不会因反常睡眠剥夺而改变。

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