Smith H J, Snowdon K E
Agriculture Canada, Health of Animals Laboratory, Sackville, New Brunswick.
Can J Vet Res. 1989 Jan;53(1):112-4.
Trichinella spiralis spiralis infections were established in sheep by administering infective larvae via gavage or feeding infected musculature. Trichinella spiralis nativa infective larvae had a low infectivity for sheep although light infections may be established in some animals with large infective doses. For the most part, sheep were averse to ingesting musculature mixed in a grain ration unless it was camouflaged with molasses. The heaviest infections usually occurred in the masseter muscle. The fact that sheep are averse to ingesting muscle tissue may reduce the likelihood of trichinosis. Anti-Trichinella antibodies to both T: spiralis spiralis and T. spiralis nativa were produced as demonstrated by the enzyme-linked immunosorbent assay. Seroconversion occurred in several sheep challenged with T. spiralis nativa even though larvae were not recovered from the musculature by pepsin-digestion.
通过经口灌喂感染性幼虫或喂食感染的肌肉组织，在绵羊中建立旋毛形线虫感染。本地旋毛形线虫的感染性幼虫对绵羊的感染性较低，尽管在一些接种大量感染性幼虫的动物中可能会建立轻度感染。在大多数情况下，绵羊不愿摄食混合在谷物日粮中的肌肉组织，除非用糖蜜掩盖。感染最严重的情况通常发生在咬肌。绵羊不愿摄食肌肉组织这一事实可能会降低旋毛虫病的发生可能性。酶联免疫吸附测定表明，绵羊产生了针对旋毛形线虫和本地旋毛形线虫的抗旋毛虫抗体。在用本地旋毛形线虫攻击的几只绵羊中发生了血清转化，尽管通过胃蛋白酶消化未从肌肉组织中回收幼虫。
