Hughes E G, Mowatt J, Spence J E
Division of Gynecology, Children's Hospital, Eastern Ontario, Ottawa.
CMAJ. 1989 Feb 1;140(3):297-301.
The highest prevalence rate of sexually transmitted chlamydial infection is among adolescent girls. To determine the rate among predominantly asymptomatic girls who were seen at a pediatric gynecology unit and to identify those at high risk we screened 541 such patients from Jan. 1 to Dec. 31, 1986, by means of direct fluorescent antibody testing; 422 (78.0%) were asymptomatic. The most common reason for presentation was a request for contraceptive advice (the reason for 59.2% of the patients). Of the 446 patients (82.4%) who were sexually active 66 (14.7%) had evidence of chlamydial infection; none of the 93 sexually inactive patients were infected. Neisseria gonorrhoeae was isolated from eight (1.5%) of the patients. The risk factors that correlated with chlamydial infection were abnormal vaginal discharge, abdominopelvic pain and an abnormal Papanicolaou test result. Because of the high morbidity rate associated with genital chlamydial infection and the high prevalence rate among adolescent girls, most of whom are asymptomatic, all sexually active teenagers should be screened.
性传播衣原体感染的最高患病率出现在青春期女孩中。为了确定在儿科妇科就诊的主要无症状女孩中的感染率,并识别高危人群,我们于1986年1月1日至12月31日期间,通过直接荧光抗体检测对541名此类患者进行了筛查;其中422名(78.0%)无症状。就诊的最常见原因是寻求避孕建议(占患者的59.2%)。在446名有性行为的患者(82.4%)中,66名(14.7%)有衣原体感染证据;93名无性行为的患者均未感染。8名(1.5%)患者分离出淋病奈瑟菌。与衣原体感染相关的危险因素有阴道分泌物异常、腹盆腔疼痛和巴氏试验结果异常。由于生殖器衣原体感染相关的发病率高,且在青春期女孩中患病率高,其中大多数无症状,所有有性行为的青少年都应接受筛查。