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[寻求避孕咨询的女性人群中宫颈沙眼衣原体感染的患病率]

[Prevalence of cervical Chlamydia trachomatis infection in a female population seeking contraception counseling].

作者信息

Boisvert R, Côté A, Poulin M, Lefebvre J

机构信息

Département de santé communautaire, Centre hospitalier Ste-Marie, Trois-Rivières, Qué.

出版信息

CMAJ. 1993 Jan 15;148(2):191-5.

Abstract

OBJECTIVES

To determine the prevalence and risk indicators of cervical infection due to Chlamydia trachomatis among female patients consulting for contraception and to evaluate an enzyme immunoassay for the detection of C. trachomatis in this setting. DESIGN: Prevalence study. Endocervical specimens were analysed by means of culture and enzyme immunoassay. C. trachomatis infection was diagnosed through culture. SETTING: A hospital family planning clinic in Trois-Rivières, Que. SUBJECTS: All 533 female patients who consulted for contraception between November 1986 and March 1988. Results of culture were available for 495 patients. MAIN OUTCOME MEASURE: Demographic, epidemiologic and clinical information was collected by means of a standard questionnaire and a gynecologic examination. MAIN RESULTS: The prevalence rate of chlamydial infection was 9% (45/495). Enzyme immunoassay detected 37 (82%) of the infections. The mean age of the patients was 19.8 years, and 98% of the infections were diagnosed in those aged 25 years or less. The variables significantly associated with C. trachomatis infection were having more than one sexual partner in the preceding year (odds ratio [OR] 2.9; 95% confidence limits [CL] 1.7 and 5.0) and having more than one partner in the preceding 3 months (OR 2.3; 95% CL 1.2 and 4.3). These two indicators would have detected 58% and 22% of the infections respectively. CONCLUSIONS: Screening for C. trachomatis infection by means of enzyme immunoassay should be proposed to all female patients aged 25 years or less consulting for contraception in our clinic. Such screening may prove to be an effective preventive measure in other similar clinical settings.

摘要

目的

确定前来咨询避孕的女性患者中沙眼衣原体宫颈感染的患病率及风险指标,并评估在此情况下用于检测沙眼衣原体的酶免疫测定法。设计:患病率研究。采用培养法和酶免疫测定法对宫颈标本进行分析。通过培养诊断沙眼衣原体感染。地点:魁北克三河城的一家医院计划生育诊所。研究对象:1986年11月至1988年3月期间前来咨询避孕的所有533名女性患者。495名患者有培养结果。主要观察指标:通过标准问卷和妇科检查收集人口统计学、流行病学和临床信息。主要结果:衣原体感染患病率为9%(45/495)。酶免疫测定法检测出37例(82%)感染。患者的平均年龄为19.8岁,98%的感染在25岁及以下的人群中被诊断出。与沙眼衣原体感染显著相关的变量是前一年有多个性伴侣(优势比[OR]2.9;95%置信区间[CL]1.7和5.0)以及前3个月有多个性伴侣(OR 2.3;95%CL 1.2和4.3)。这两个指标分别能检测出58%和22%的感染。结论:对于在我们诊所咨询避孕的所有25岁及以下女性患者,应建议采用酶免疫测定法筛查沙眼衣原体感染。这种筛查在其他类似临床环境中可能被证明是一种有效的预防措施。

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